Iron and copper transport in yeast and its relevance to human disease

被引：188

作者：

Askwith, C ^{[1
]}

Kaplan, J ^{[1
]}

机构：

[1] Univ Utah, Dept Pathol, Salt Lake City, UT 84132 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 04期

关键词：

D O I：

10.1016/S0968-0004(98)01192-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent progress in the field of copper and iron metabolism has resulted from a convergence of human and yeast genetics. The mechanisms of iron and copper transport are remarkably conserved between yeast and humans. Studies of the yeast homologs of human disease genes involved in metal homeostasis have shed light on the pathophysiology of these disorders.

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页码：135 / 138

页数：4

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