NF-κB transcription factors:: critical regulators of hematopoiesis and neuronal survival

被引：111

作者：

Denk, A ^{[1
]}

Wirth, T ^{[1
]}

Baumann, B ^{[1
]}

机构：

[1] Univ Ulm, Dept Physiol Chem, D-89081 Ulm, Germany

来源：

CYTOKINE & GROWTH FACTOR REVIEWS | 2000年 / 11卷 / 04期

关键词：

NF-kappa B; hematopoiesis; apoptosis; neuronal survival; signal transduction;

D O I：

10.1016/S1359-6101(00)00009-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Rel/NF-kappa B family of transcription factors has been implicated in the regulation of genes involved in immune and inflammatory responses. and of processes such as cell survival, apoptosis, development, differentiation, cell growth and neoplastic transformation. In this report we will summarize recent findings which highlight critical roles of NF-KB in different processes in hematopoietic and neuronal cells. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：303 / 320

页数：18

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