Lymphangiogenesis - New mechanisms

被引：50

作者：

Chang, L

Kaipainen, A

Folkman, J

机构：

[1] Childrens Hosp, Surg Res Lab, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Surg, Boston, MA 02115 USA

来源：

LYMPHATIC CONTINUUM: LYMPHATIC BIOLOGY AND DISEASE | 2002年 / 979卷

关键词：

angiogenesis; lymphangiogenesis; bFGF; VEGF-A; VEGF-D; angiogenesis inhibitor; lymph angiogenesis inhibitor; lymphatic endothelial cells; blood vessel endothelial cells; murine cornea neovascularization;

D O I：

10.1111/j.1749-6632.2002.tb04872.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A mouse model has been developed to study lymphangiogenesis dissociated from angiogenesis. bFGF implanted in a mouse cornea at a concentration below the threshold to induce angiogenesis potently induces lymphangiogenesis. This model has permitted a study of cellular and molecular mechanisms of lymphangiogenesis.

引用

页码：111 / 119

页数：9

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