Magnetic resonance assessment of acute and chronic stroke

被引：10

作者：

Welch, KMA

Cao, Y

Nagesh, V

机构：

[1] Henry Ford Hlth Sci Ctr, Dept Neurol, NMR Res Lab, Detroit, MI 48202 USA

[2] NMR Res Ctr, Detroit, MI 48202 USA

[3] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA

[4] Michigan State Univ, Dept Radiol, E Lansing, MI 48824 USA

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2000年 / 43卷 / 02期

关键词：

D O I：

10.1053/pcad.2000.9029

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This article describes the important role of magnetic resonance imaging (MRI) in noninvasively assessing human focal ischemic stroke. Conventional MRI, diffusion-weighted and/or perfusion-weighted imaging have been used to facilitate both the qualitative and quantitative evaluation of heterogeneity of ischemic brain tissue. Further, by combining 2 or more magnetic resonance parameters, tissue-signature models have been developed that may be used as surrogate markers of tissue histopathology to characterize ischemic tissue as salvageable, necrotic, or tissue in transition to necrosis. Magnetic resonance tissue-signature models and results are presented. Dynamic changes in the evolution of ischemic tissue to infarction are also discussed. Recovery from acute stroke was studied with blood oxygenation level-dependent functional MRI to investigate the neural mechanisms for recovery from aphasia after stroke. Copyright (C) 2000 by W.B. Saunders Company.

引用

页码：113 / 134

页数：22

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