Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke

被引：150

作者：

Hill, MD ^{[1
]}

Lye, T ^{[1
]}

Moss, H ^{[1
]}

Barber, PA ^{[1
]}

Demchuk, AM ^{[1
]}

Newcommon, NJ ^{[1
]}

Green, TL ^{[1
]}

Kenney, C ^{[1
]}

Cole-Haskayne, A ^{[1
]}

Buchan, AM ^{[1
]}

机构：

[1] Univ Calgary, Foothills Hosp, Dept Clin Neurosci, Calgary Stroke Program, Calgary, AB T2N 2T9, Canada

来源：

NEUROLOGY | 2003年 / 60卷 / 09期

关键词：

D O I：

10.1212/01.WNL.0000058840.66596.1A

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

One hundred seventy-six consecutive patients treated with IV tissue plasminogen activator (tPA) for acute ischemic stroke were examined prospectively, and orolingual angioedema was found in nine (5.1%; 95% CI 2.3 to 9.5). The reaction was typically mild, transient, and contralateral to the ischemic hemisphere. Risk of angioedema was associated with angiotensin-converting enzyme inhibitors (relative risk [RR] 13.6; 95% CI 3.0 to 62.7) and signs on initial CT of ischemia in the insular and frontal cortex (RR 9.1; 95% CI 1.4 to 30.0).

引用

页码：1525 / 1527

页数：3

共 10 条

[1] Angioedema due to angiotensin-converting enzyme inhibitors [J].