Aberrant methylation of gene promoters in cancer - Concepts, misconcepts, and promise

被引：112

作者：

Baylin, SB

Belinsky, SA

Herman, JG

机构：

[1] Johns Hopkins Med Inst, Baltimore, MD 21205 USA

[2] Ctr Comprehens Canc, Baltimore, MD USA

[3] Lovelace Resp Res Inst, Albuquerque, NM USA

来源：

JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2000年 / 92卷 / 18期

关键词：

D O I：

10.1093/jnci/92.18.1460

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：1460 / 1461

页数：2

共 17 条

[1] DNA hypermethylation in tumorigenesis - epigenetics joins genetics [J].

Baylin, SB ;

Herman, JG .

TRENDS IN GENETICS, 2000, 16 (04) :168-174

[2] Methylation-induced repression - Belts, braces, and chromatin [J].

Bird, AP ;

Wolffe, AP .

CELL, 1999, 99 (05) :451-454

[3] Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer [J].

Cameron, EE ;

Bachman, KE ;

Myöhänen, S ;

Herman, JG ;

Baylin, SB .

NATURE GENETICS, 1999, 21 (01) :103-107

[4] Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors [J].

Esteller, M ;

Silva, JM ;

Dominguez, G ;

Bonilla, F ;

Matias-Guiu, X ;

Lerma, E ;

Bussaglia, E ;

Prat, J ;

Harkes, IC ;

Repasky, EA ;

Gabrielson, E ;

Schutte, M ;

Baylin, SB ;

Herman, JG .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (07) :564-569

[5] BRCA1 and E-cadherin promoter hypermethylation and gene inactivation in cancer-association or mechanism? [J].

Fearon, ER .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (07) :515-517

[6] Facile detection of mitochondrial DNA mutations in tumors and bodily fluids [J].

Fliss, MS ;

Usadel, H ;

Cabellero, OL ;

Wu, L ;

Buta, MR ;

Eleff, SM ;

Jen, J ;

Sidransky, D .

SCIENCE, 2000, 287 (5460) :2017-2019

[7] DNA methyltransferase Dnmt1 associates with histone deacetylase activity [J].

Fuks, F ;

Burgers, WA ;

Brehm, A ;

Hughes-Davies, L ;

Kouzarides, T .

NATURE GENETICS, 2000, 24 (01) :88-91

[8] Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma [J].

Herman, JG ;

Umar, A ;

Polyak, K ;

Graff, JR ;

Ahuja, N ;

Issa, JPJ ;

Markowitz, S ;

Willson, JKV ;

Hamilton, SR ;

Kinzler, KW ;

Kane, MF ;

Kolodner, RD ;

Vogelstein, B ;

Kunkel, TA ;

Baylin, SB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :6870-6875

[9] Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands [J].

Herman, JG ;

Graff, JR ;

Myohanen, S ;

Nelkin, BD ;

Baylin, SB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) :9821-9826

[10] DAP kinase links the control of apoptosis to metastasis [J].

Inbal, B ;

Cohen, O ;

PolakCharcon, S ;

Kopolovic, J ;

Vadai, E ;

Eisenbach, L ;

Kimchi, A .

NATURE, 1997, 390 (6656) :180-184

← 1 2 →