Single walled carbon nanotubes for transport and delivery of biological cargos

被引：75

作者：

Kam, Nadine Wong Shi ^{[1
]}

Dai, Hongjie

机构：

[1] Univ Michigan, Michigan Soc Fellows, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA

[3] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS | 2006年 / 243卷 / 13期

关键词：

D O I：

10.1002/pssb.200669226

中图分类号：

O469 [凝聚态物理学];

学科分类号：

070205 ;

摘要：

The innate ability of carbon nanotubes to breach the cell membrane of various types of mammalian cells has been reported. Here, we present a summary of the various applications of carbon nanotubes as a cellular transport and delivery system for functional biological cargos. The internalization of SWNTs for transport and delivery into cells is mediated via endocytosis and does not appear to have any detrimental effect on either the transported cargo or the breached cell. The emergence of SWNT as a new class of cellular transporters holds many exciting promises for SWNT-based systems for drug delivery, protein delivery, gene therapy and cancer therapy applications. (c) 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3561 / 3566

页数：6

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