Platelet-leukocyte interactions in inflammation and atherothrombosis

被引：79

作者：

May, Andreas E. ^{[1
]}

Langer, Harald ^{[1
]}

Seizer, Peter ^{[1
]}

Bigalke, Boris ^{[1
]}

Lindemann, Stephan ^{[1
]}

Gawaz, Meinrad ^{[1
]}

机构：

[1] Univ Tubingen, Med Klin 3, D-72076 Tubingen, Germany

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2007年 / 33卷 / 02期

关键词：

platelets; inflammation; atherothrombosis; leukocytes; chemokines;

D O I：

10.1055/s-2007-969023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Inflammatory processes at the vascular wall result in the development of atherosclerosis. Platelet interactions with leukocytes may play a key role in the initiation of inflammation. They trigger autocrine and paracrine activation processes, leading to leukocyte recruitment (in)to the vascular wall. This article highlights the molecular basis and the inflammatory pathways initiated by platelet-leukocyte interactions.

引用

页码：123 / 127

页数：5

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