The ENCODE (ENCyclopedia of DNA elements) Project

被引:1722
作者
Feingold, EA [1 ]
Good, PJ [1 ]
Guyer, MS [1 ]
Kamholz, S [1 ]
Liefer, L [1 ]
Wetterstrand, K [1 ]
Collins, FS [1 ]
Gingeras, TR [1 ]
Kampa, D [1 ]
Sekinger, EA [1 ]
Cheng, J [1 ]
Hirsch, H [1 ]
Ghosh, S [1 ]
Zhu, Z [1 ]
Pate, S [1 ]
Piccolboni, A [1 ]
Yang, A [1 ]
Tammana, H [1 ]
Bekiranov, S [1 ]
Kapranov, P [1 ]
Harrison, R [1 ]
Church, G [1 ]
Struhl, K [1 ]
Ren, B [1 ]
Kim, TH [1 ]
Barrera, LO [1 ]
Qu, C [1 ]
Van Calcar, S [1 ]
Luna, R [1 ]
Glass, CK [1 ]
Rosenfeld, MG [1 ]
Guigo, R [1 ]
Antonarakis, SE [1 ]
Birney, E [1 ]
Brent, M [1 ]
Pachter, L [1 ]
Reymond, A [1 ]
Dermitzakis, ET [1 ]
Dewey, C [1 ]
Keefe, D [1 ]
Denoeud, F [1 ]
Lagarde, J [1 ]
Ashurst, J [1 ]
Hubbard, T [1 ]
Wesselink, JJ [1 ]
Castelo, R [1 ]
Eyras, E [1 ]
Myers, RM [1 ]
Sidow, A [1 ]
Batzoglou, S [1 ]
机构
[1] NHGRI, Bethesda, MD 20892 USA
关键词
D O I
10.1126/science.1105136
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements in the human genome sequence. The pilot phase of the Project is focused on a specified 30 megabases (similar to1%) of the human genome sequence and is organized as an international consortium of computational and laboratory-based scientists working to develop and apply high-throughput approaches for detecting all sequence elements that confer biological function. The results of this pilot phase will guide future efforts to analyze the entire human genome.
引用
收藏
页码:636 / 640
页数:5
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