Endometrial CD56+natural killer cells in women with recurrent miscarriage: a histomorphometric study

被引：176

作者：

Clifford, K

Flanagan, AM

Regan, L

机构：

[1] St Marys Hosp, Imperial Coll Sch Med, Dept Obstet & Gynaecol, London W2 1NY, England

[2] St Marys Hosp, Imperial Coll Sch Med, Dept Histopathol, London W2 1NY, England

来源：

HUMAN REPRODUCTION | 1999年 / 14卷 / 11期

关键词：

endometrium; natural killer cells; recurrent miscarriage;

D O I：

10.1093/humrep/14.11.2727

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Endometrial natural killer (NK) cells were compared in luteal-phase endometrial samples from women,vith recurrent miscarriage and from normal subjects. Cryostat sections were labelled using a monoclonal antibody to CD56 using an avidin-biotin complex method and a morphometric study performed. Increased mean numbers of CD56+ cells were documented in the endometrium of women with recurrent early miscarriage only. These findings suggest a possible role for NK cells in the pathogenesis of recurrent early pregnancy loss.

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页码：2727 / 2730

页数：4

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