Enabling proteomics: the need for an extendable 'workbench' for user-configurable solutions

被引:2
作者
Beynon, RJ [1 ]
机构
[1] Univ Liverpool, Robert J Beynon Dept Vet Preclin Sci, Liverpool L69 7ZJ, Merseyside, England
来源
COMPARATIVE AND FUNCTIONAL GENOMICS | 2004年 / 5卷 / 01期
关键词
proteomics; mass spectrometry; bioinformatics;
D O I
10.1002/cfg.372
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Proteomics has the capability to generate overwhelming quantities of data in relatively short timescales, and it is not uncommon to see experimenters investing substantially more time in data analysis than in data gathering. Although several sophisticated tools for data reduction and analysis are available, they lack the flexibility to cope with increasingly innovative experimental strategies and new database resources that encode both qualitative and quantitative data. I will outline a specification of a flexible proteomics tool that could address many current bottlenecks and deficiencies. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码:52 / 55
页数:4
相关论文
共 6 条
[1]   The proteomics standards initiative [J].
Orchard, S ;
Hermjakob, H ;
Apweiler, R .
PROTEOMICS, 2003, 3 (07) :1374-1376
[2]   Meeting review: Progress in establishing common standards for exchanging proteomics data: the second meeting of the HUPO proteomics standards initiative [J].
Orchard, S ;
Kersey, P ;
Zhu, WM ;
Montecchi-Palazzi, L ;
Hermjakob, H ;
Apweiler, R .
COMPARATIVE AND FUNCTIONAL GENOMICS, 2003, 4 (02) :203-206
[3]   Dynamics of protein turnover, a missing dimension in proteomics [J].
Pratt, JM ;
Petty, J ;
Riba-Garcia, I ;
Robertson, DHL ;
Gaskell, SJ ;
Oliver, SG ;
Beynon, RJ .
MOLECULAR & CELLULAR PROTEOMICS, 2002, 1 (08) :579-591
[4]  
Pratt JM, 2002, PROTEOMICS, V2, P157, DOI 10.1002/1615-9861(200202)2:2<157::AID-PROT157>3.0.CO
[5]  
2-M
[6]   A systematic approach to modeling, capturing, and disseminating proteomics experimental data [J].
Taylor, CF ;
Paton, NW ;
Garwood, KL ;
Kirby, PD ;
Stead, DA ;
Yin, ZK ;
Deutsch, EW ;
Selway, L ;
Walker, J ;
Riba-Garcia, I ;
Mohammed, S ;
Deery, MJ ;
Howard, JA ;
Dunkley, T ;
Aebersold, R ;
Kell, DB ;
Lilley, KS ;
Roepstorff, P ;
Yates, JR ;
Brass, A ;
Brown, AJP ;
Cash, P ;
Gaskell, SJ ;
Hubbard, SJ ;
Oliver, SG .
NATURE BIOTECHNOLOGY, 2003, 21 (03) :247-254