Neuroprotective Protein and Carboxypeptidase E

被引：16

作者：

Koshimizu, Hisatsugu ^{[1
]}

Senatorov, Vladimir ^{[1
]}

Loh, Y. Peng ^{[1
]}

Gozes, Illana ^{[2
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Cellular Neurobiol Sect, Program Dev Neurosci, NIH, Bethesda, MD 20892 USA

[2] Tel Aviv Univ, Sackler Fac Med, Dept Human Mol Genet & Biochem, Elton Lab Mol Neuoendocrinol, IL-69978 Tel Aviv, Israel

来源：

JOURNAL OF MOLECULAR NEUROSCIENCE | 2009年 / 39卷 / 1-2期

关键词：

ACTIVITY-DEPENDENT SECRETION; TRANSGENIC MOUSE MODEL; NEUROTROPHIC FACTOR; SUBCELLULAR-LOCALIZATION; TAU-HYPERPHOSPHORYLATION; ALZHEIMERS-DISEASE; PEPTIDE; BRAIN; NEURONS; ADNP;

D O I：

10.1007/s12031-008-9164-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review outlines the neuroprotective activities and structural specificities of two distinct proteins, activity-dependent neuroprotective protein, a protein assigned transcription factor/chromatin remodeling activity, and carboxypeptidase E, a classic exopeptidase. Future studies will elucidate how these two versatile proteins converge onto a similar endpoint: neuroprotection.

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页码：1 / 8

页数：8

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