The Gene Ontology (GO) project in 2006

被引：840

作者：

Harris, Midori A. ^{[1
]}

Clark, Jennifer I. ^{[1
]}

Ireland, Amelia ^{[1
]}

Lomax, Jane ^{[1
]}

Ashburner, Michael ^{[1
]}

Collins, Russell ^{[1
]}

Eilbeck, Karen ^{[1
]}

Lewis, Suzanna ^{[1
]}

Mungall, Chris ^{[1
]}

Richter, John ^{[1
]}

Rubin, Gerald M. ^{[1
]}

Shu, ShengQiang ^{[1
]}

Blake, Judith A. ^{[1
]}

Bult, Carol J. ^{[1
]}

Diehl, Alexander D. ^{[1
]}

Dolan, Mary E. ^{[1
]}

Drabkin, Harold J. ^{[1
]}

Eppig, Janan T. ^{[1
]}

Hill, David P. ^{[1
]}

Ni, Li ^{[1
]}

Ringwald, Martin ^{[1
]}

Balakrishnan, Rama ^{[1
]}

Binkley, Gail ^{[1
]}

Cherry, J. Michael ^{[1
]}

Christie, Karen R. ^{[1
]}

Costanzo, Maria C. ^{[1
]}

Dong, Qing ^{[1
]}

Engel, Stacia R. ^{[1
]}

Fisk, Dianna G. ^{[1
]}

Hirschman, Jodi E. ^{[1
]}

Hitz, Benjamin C. ^{[1
]}

Hong, Eurie L. ^{[1
]}

Lane, Christopher ^{[1
]}

Miyasato, Stuart ^{[1
]}

Nash, Robert ^{[1
]}

Sethuraman, Anand ^{[1
]}

Skrzypek, Marek ^{[1
]}

Theesfeld, Chandra L. ^{[1
]}

Weng, Shuai ^{[1
]}

Botstein, David ^{[1
]}

Dolinski, Kara ^{[1
]}

Oughtred, Rose ^{[1
]}

Berardini, Tanya ^{[1
]}

Mundodi, Suparna ^{[1
]}

Rhee, Seung Y. ^{[1
]}

Apweiler, Rolf ^{[1
]}

Barrell, Daniel ^{[1
]}

Camon, Evelyn ^{[1
]}

Dimmer, Emily ^{[1
]}

Mulder, Nicola ^{[1
]}

机构：

[1] EMBL EBI, GO EBI, Hinxton CB10 1SD, Cambs, England

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkj021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Gene Ontology (GO) project (http://www.geneontology.org) develops and uses a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://song.sourceforge.net/). The GO Consortium continues to improve to the vocabulary content, reflecting the impact of several novel mechanisms of incorporating community input. A growing number of model organism databases and genome annotation groups contribute annotation sets using GO terms to GO's public repository. Updates to the AmiGO browser have improved access to contributed genome annotations. As the GO project continues to grow, the use of the GO vocabularies is becoming more varied as well as more widespread. The GO project provides an ontological annotation system that enables biologists to infer knowledge from large amounts of data.

引用

页码：D322 / D326

页数：5

共 36 条

[1]

Ashburner M, 2001, GENOME RES, V11, P1425

[2] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[3]

BLAKE J, 2003, CURRENT PROTOCOLS BI

[4] The Unified Medical Language System (UMLS): integrating biomedical terminology [J].

Bodenreider, O .

NUCLEIC ACIDS RESEARCH, 2004, 32 :D267-D270

[5] The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene Ontology [J].

Camon, E ;

Magrane, M ;

Barrell, D ;

Lee, V ;

Dimmer, E ;

Maslen, J ;

Binns, D ;

Harte, N ;

Lopez, R ;

Apweiler, R .

NUCLEIC ACIDS RESEARCH, 2004, 32 :D262-D266

[6]

Camon EB, 2005, BMC BIOINFORMATICS, V6, DOI 10.1186/1471-2105-6-S1-S17

[7] An ontology for collaborative construction and analysis of cellular pathways [J].

Demir, E ;

Babur, O ;

Dogrusoz, U ;

Gursoy, A ;

Ayaz, A ;

Gulesir, G ;

Nisanci, G ;

Cetin-Atalay, R .

BIOINFORMATICS, 2004, 20 (03) :349-356

[8] A procedure for assessing GO annotation consistency [J].

Dolan, ME ;

Ni, L ;

Camon, E ;

Blake, JA .

BIOINFORMATICS, 2005, 21 :I136-I143

[9] Sequence Ontology Annotation Guide [J].

Eilbeck, K ;

Lewes, SE .

COMPARATIVE AND FUNCTIONAL GENOMICS, 2004, 5 (08) :642-647

[10] The Sequence Ontology: a tool for the unification of genome annotations [J].

Eilbeck, K ;

Lewis, SE ;

Mungall, CJ ;

Yandell, M ;

Stein, L ;

Durbin, R ;

Ashburner, M .

GENOME BIOLOGY, 2005, 6 (05)

← 1 2 3 4 →