Subdiffusion and anomalous local viscoelasticity in actin networks

被引:418
作者
Amblard, F
Maggs, AC
Yurke, B
Pargellis, AN
Leibler, S
机构
[1] PRINCETON UNIV,DEPT MOL BIOL,PRINCETON,NJ 08544
[2] PRINCETON UNIV,DEPT PHYS,PRINCETON,NJ 08544
[3] AT&T BELL LABS,MURRAY HILL,NJ 07974
关键词
D O I
10.1103/PhysRevLett.77.4470
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We use magnetic tweezers to study local viscoelastic response in filamentous actin networks. The choice of magnetic, colloidal particles of varying size allows us to explore properties on the relevant micron and submicron scales. At these scales the mechanical response is determined by the bending properties of individual filaments and described by an anomalous power-law behavior. In the absence of external forces the particles exhibit a subdiffusive motion.
引用
收藏
页码:4470 / 4473
页数:4
相关论文
共 20 条
[1]   A magnetic manipulator for studying local rheology and micromechanical properties of biological systems [J].
Amblard, F ;
Yurke, B ;
Pargellis, A ;
Leibler, S .
REVIEW OF SCIENTIFIC INSTRUMENTS, 1996, 67 (03) :818-827
[2]   MAKING LIGHT WORK WITH OPTICAL TWEEZERS [J].
BLOCK, SM .
NATURE, 1992, 360 (6403) :493-495
[3]  
Bray D., 1992, CELL MOVEMENTS
[4]   THE PHYSICAL PROPERTIES OF CYTOPLASM - A STUDY BY MEANS OF THE MAGNETIC PARTICLE METHOD .1. EXPERIMENTAL [J].
CRICK, FHC ;
HUGHES, AFW .
EXPERIMENTAL CELL RESEARCH, 1950, 1 (01) :37-80
[5]   DYNAMIC SCATTERING FROM SEMIFLEXIBLE POLYMERS [J].
FARGE, E ;
MAGGS, AC .
MACROMOLECULES, 1993, 26 (19) :5041-5044
[6]  
Ferry D.J., 1980, Viscoelastic Properties of Polymers, V3e
[7]   FLEXURAL RIGIDITY OF MICROTUBULES AND ACTIN-FILAMENTS MEASURED FROM THERMAL FLUCTUATIONS IN SHAPE [J].
GITTES, F ;
MICKEY, B ;
NETTLETON, J ;
HOWARD, J .
JOURNAL OF CELL BIOLOGY, 1993, 120 (04) :923-934
[8]  
Heilbronn A., 1922, JB WISS BOT, V61, P284
[9]   BROWNIAN-MOTION OF INERT TRACER MACROMOLECULES IN POLYMERIZED AND SPONTANEOUSLY BUNDLED MIXTURES OF ACTIN AND FILAMIN [J].
HOU, L ;
LUBYPHELPS, K ;
LANNI, F .
JOURNAL OF CELL BIOLOGY, 1990, 110 (05) :1645-1654
[10]  
JANMEY PA, 1991, CURR OPIN CELL BIOL, V2, P11