Use of Statin During Hospitalization Improves the Outcome After Intracerebral Hemorrhage

AimsTo examine the relationship between statin use in Chinese patients with intracerebral hemorrhage (ICH) during their hospitalization and the outcomes. MethodsData were collected from the China National Stroke Registry. Good functional outcome was defined by a modified Rankin Scale score between 0-2. Functional outcome and rate of mortality at 3months and 1year were compared between ICH patients on statin and those without it during their hospitalization. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated using the multivariable logistic regression model adjusted for baseline risk factors. ResultsAmong 3218 consecutive ICH patients from 2007 to 2008, 220 (6.8%) were on statin during their hospitalization. Compared with those without statin, patients on statin were younger, had more stroke risk factors but lower stroke severity. ICH patients on statin had better functional outcome at 3months (OR 2.24, 95% CI 1.49-3.36) and at 1year (OR 2.04, 95% CI 1.37-3.06). They also had lower rate of mortality at 3months (OR 0.44, 95% CI 0.22-0.87) and 1year (OR 0.49, 95% CI 0.27-0.86). ConclusionsIn-hospital statin use in ICH patients is associated with better functional outcome and lower mortality at 3months and 1year.