No evidence of hypoxic tissue on 18F-fluoromisonidazole PET after intracerebral hemorrhage

被引：60

作者：

Hirano, T ^{[1
]}

Read, SJ ^{[1
]}

Abbott, DF ^{[1
]}

Sachinidis, JI ^{[1
]}

Tochon-Danguy, HJ ^{[1
]}

Egan, GF ^{[1
]}

Bladin, CF ^{[1
]}

Scott, AM ^{[1
]}

McKay, WJ ^{[1
]}

Donnan, GA ^{[1
]}

机构：

[1] Univ Melbourne, Dept Med, Parkville, Vic 3052, Australia

来源：

NEUROLOGY | 1999年 / 53卷 / 09期

关键词：

cerebral hemorrhage; positron emission tomography; nitroimidazoles;

D O I：

10.1212/WNL.53.9.2179

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied six patients after intracerebral hemorrhage (ICH) and eight controls using positron emission tomography (PET) with to determine whether a zone of tissue hypoxia, possibly representing "penumbral" tissue, exists surrounding an intracerebral hemorrhage. None of the stroke patients, studied 24 to 43 hours after symptom onset, nor any of the controls exhibited areas of tissue hypoxia on F-18-fluoromisonidazole PET images. These findings may have implications for the treatment of intracerebral hemorrhage with neuroprotective strategies.

引用

页码：2179 / 2182

页数：4

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