Stem cells for the treatment of neurological disorders

被引：626

作者：

Lindvall, O ^{[1
]}

Kokaia, Z

机构：

[1] Univ Lund Hosp, Wallenberg Neurosci Ctr, Sect Restorat Neurol, Lab Neurogenesis & Cell Therapy, SE-22184 Lund, Sweden

[2] Univ Lund Hosp, Stem Cell Inst, Sect Restorat Neurol, Lab Neural Stem Cell Biol, SE-22184 Lund, Sweden

[3] Lund Strateg Res Ctr Stem Cell Biol & Cell Therap, Lund, Sweden

来源：

NATURE | 2006年 / 441卷 / 7097期

关键词：

D O I：

10.1038/nature04960

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Many common neurological disorders, such as Parkinson's disease, stroke and multiple sclerosis, are caused by a loss of neurons and glial cells. In recent years, neurons and glia have been generated successfully from stem cells in culture, fuelling efforts to develop stem-cell-based transplantation therapies for human patients. More recently, efforts have been extended to stimulating the formation and preventing the death of neurons and glial cells produced by endogenous stem cells within the adult central nervous system. The next step is to translate these exciting advances from the laboratory into clinically useful therapies.

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收藏

页码：1094 / 1096

页数：3

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