The HP1 protein family: getting a grip on chromatin

被引：390

作者：

Eissenberg, JC

Elgin, SCR

机构：

[1] St Louis Univ, Sch Med, Dept Biochem & Mol Biol, St Louis, MO 63104 USA

[2] Washington Univ, Dept Biol, St Louis, MO 63130 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2000年 / 10卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-437X(00)00058-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

HP1 was first described in Drosophila as a heterochromatin-associated protein with dosage-dependent effects on heterochromatin-induced gene silencing, Recently, membership of the HP1 protein family has expanded tremendously. A number of intriguing interactions between HP1 and other proteins have been described, implicating HP1 in gene regulation, DNA replication, and nuclear architecture.

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收藏

页码：204 / 210

页数：7

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