Nogo on the go

被引：110

作者：

McKerracher, L ^{[1
]}

Winton, MJ ^{[1
]}

机构：

[1] Univ Montreal, Dept Pathol & Biol Cellulaire, Montreal, PQ H3T 1J4, Canada

来源：

NEURON | 2002年 / 36卷 / 03期

关键词：

D O I：

10.1016/S0896-6273(02)01018-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Growth inhibition in the central nervous system (CNS) is a major barrier to axon regeneration. Recent findings indicate that three distinct myelin proteins, myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte-myelin glycoprotein (OMgp), inhibit axon growth by binding a common receptor, the Nogo66 receptor (NgR), and likely converge on a common signaling cascade.

引用

页码：345 / 348

页数：4

共 20 条

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