How well does ASPECTS predict the outcome of acute stroke treated with IV tPA?

被引：47

作者：

Weir, Nicolas U. ^{[1
]}

Warwick Pexman, J. H. ^{[1
]}

Hill, Michael D. ^{[1
]}

Buchan, Alastair M. ^{[1
]}

机构：

[1] Univ Calgary, Dept Clin Neurosci, Calgary Stroke Program, Calgary, AB, Canada

来源：

NEUROLOGY | 2006年 / 67卷 / 03期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1212/01.wnl.0000228221.44334.73

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors measured the association of early ischemic change on CT scan, measured using the Alberta Stroke Programme Early CT score ( ASPECTS), and functional outcome in 825 patients with anterior circulation stroke treated with IV thrombolysis within 3 hours of onset. ASPECTS predicted outcome in a graded fashion ( linearly for ASPECTS 6 through 10; pattern ill-defined for ASPECTS 0 through 5) but discriminated individual outcomes weakly. Except perhaps when early ischemic change is extensive, clinicians should not estimate prognosis using ASPECTS alone.

引用

页码：516 / 518

页数：3

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