Prognostic implications of admission inflammatory profile in acute ischemic neurological events

被引：52

作者：

Anuk, T

Assayag, EB

Rotstein, R

Fusman, R

Zeltser, D

Berliner, S

Avitzour, D

Shapira, I

Arber, N

Bornstein, NM

机构：

[1] Tel Aviv Sourasky Med Ctr, Dept Internal Med D, IL-64239 Tel Aviv, Israel

[2] Tel Aviv Sourasky Med Ctr, Stroke Unit, IL-64239 Tel Aviv, Israel

[3] Tel Aviv Sourasky Med Ctr, Dept Neurol, IL-64239 Tel Aviv, Israel

[4] Timorim Comp Technol, Jerusalem, Israel

[5] Tel Aviv Sourasky Med Ctr, Dept Gastroenterol, IL-64239 Tel Aviv, Israel

来源：

ACTA NEUROLOGICA SCANDINAVICA | 2002年 / 106卷 / 04期

关键词：

inflammation; acute ischemic neurological event; high-sensitive C-reactive protein;

D O I：

10.1034/j.1600-0404.2002.01224.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective - To reveal the potential prognostic implications of admission inflammatory markers in patients with acute ischemic neurological events. Patients and methods - Sixty patients with an acute ischemic neurological event who were examined within 24 h from the appearance of symptomatology. We determined the high-sensitive C-reactive protein (hs-CRP) concentrations, erythrocyte sedimentation rate (ESR), fibrinogen concentrations and degree of erythrocyte adhesiveness/aggregation. Results - A significant correlation was noted between baseline hs-CRP concentrations, ESR as well as adhesiveness/aggregation and the outcome of the ischemic neurological event as determined by the modified Rankin scale 8-12 months following the insult. Conclusion - Admission inflammatory markers have long-term prognostic implications in patients with acute ischemic neurological events. These findings are relevant in view of the new therapeutic interventions now available for reducing the inflammatory response.

引用

页码：196 / 199

页数：4

共 18 条

[1] Combined leukocyte and erythrocyte aggregation in the peripheral venous blood during sepsis. An indication of commonly shared adhesive protein(s) [J].