Chemokines in tissue-specific and microenvironment-specific lymphocyte homing

被引：528

作者：

Campbell, JJ

Butcher, EC

机构：

[1] Harvard Univ, Sch Med, Dept Pathol, Childrens Hosp, Boston, MA 02115 USA

[2] Stanford Univ, Sch Med, Dept Pathol, Lab Immunol & Vasc Biol, Stanford, CA 94305 USA

[3] Vet Affairs Med Ctr, Ctr Mol Biol & Med, Palo Alto, CA 94304 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(00)00096-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This review describes recent breakthroughs in our understanding of the roles played by chemokines in lymphocyte trafficking. These include the first demonstration that chemokines control lymphocyte/vascular recognition by shear-resistant rapid adhesion; the first example of specialized tissue-specific homing mediated by chemokines; and the implication that chemokines may control microenvironmental segregation within lymphoid organs.

引用

收藏

页码：336 / 341

页数：6

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