Calcineurin: a central controller of signalling in eukaryotes - Workshop on the calcium/calcineurin/NFAT pathway: Regulation and function

被引:128
作者
Aramburu, J
Heitman, J
Crabtree, GR
机构
[1] Univ Pompeu Fabra, Dept Ciencies Expt Salut, Barcelona 08003, Spain
[2] Duke Univ, Med Ctr, Howard Hughes Med Inst, Dept Mol Genet & Microbiol, Durham, NC 27710 USA
[3] Stanford Univ, Howard Hughes Med Inst, Beckman Ctr, Stanford, CA 94305 USA
关键词
calcineurin; calcipressins; NFAT proteins; transcription;
D O I
10.1038/sj.embor.7400133
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:343 / 348
页数:6
相关论文
共 18 条
[1]   Calcineurin is essential for Candida albicans survival in serum and virulence [J].
Blankenship, JR ;
Wormley, FL ;
Boyce, MK ;
Schell, WA ;
Filler, SG ;
Perfect, JR ;
Heitman, J .
EUKARYOTIC CELL, 2003, 2 (03) :422-430
[2]   Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis [J].
Chuvpilo, S ;
Jankevics, E ;
Tyrsin, D ;
Akimzhanov, A ;
Moroz, D ;
Jha, MK ;
Luehrmann, JS ;
Santner-Nanan, B ;
Feoktistova, E ;
König, T ;
Avots, A ;
Schmitt, E ;
Berberich-Siebelt, F ;
Schimpl, A ;
Serfling, E .
IMMUNITY, 2002, 16 (06) :881-895
[3]   Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life [J].
Genescà, L ;
Aubareda, A ;
Fuentes, JJ ;
Estivill, X ;
De la Luna, S ;
Pérez-Riba, M .
BIOCHEMICAL JOURNAL, 2003, 374 (02) :567-575
[4]   Signals transduced by Ca2+/calcineurin and NFATc3/c4 pattern the developing vasculature [J].
Graef, IA ;
Chen, F ;
Chen, L ;
Kuo, A ;
Crabtree, GR .
CELL, 2001, 105 (07) :863-875
[5]   L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons [J].
Graef, IA ;
Mermelstein, PG ;
Stankunas, K ;
Neilson, JR ;
Deisseroth, K ;
Tsien, RW ;
Crabtree, GR .
NATURE, 1999, 401 (6754) :703-708
[6]   Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins [J].
Heissmeyer, V ;
Macián, F ;
Im, SH ;
Varma, R ;
Feske, S ;
Venuprasad, K ;
Gu, H ;
Liu, YC ;
Dustin, ML ;
Rao, A .
NATURE IMMUNOLOGY, 2004, 5 (03) :255-265
[7]   Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A:: Roles of the nuclear factor of activated T cells and cyclooxygenase 2 [J].
Hernández, GL ;
Volpert, OV ;
Iñiguez, MA ;
Lorenzo, E ;
Martínez-Martínez, S ;
Grau, R ;
Fresno, M ;
Redondo, JM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 193 (05) :607-620
[8]   GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs [J].
Hilioti, Z ;
Gallagher, DA ;
Low-Nam, ST ;
Ramaswamy, P ;
Gajer, P ;
Kingsbury, TJ ;
Birchwood, CJ ;
Levchenko, A ;
Cunningham, KW .
GENES & DEVELOPMENT, 2004, 18 (01) :35-47
[9]   Negative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase I [J].
Kafadar, KA ;
Zhu, H ;
Snyder, M ;
Cyert, MS .
GENES & DEVELOPMENT, 2003, 17 (21) :2698-2708
[10]   Negative regulation and gain control of sensory neurons by the C-elegans calcineurin TAX-6 [J].
Kuhara, A ;
Inada, H ;
Katsura, I ;
Mori, I .
NEURON, 2002, 33 (05) :751-763