New animal models for Parkinson's disease

被引：78

作者：

Dawson, TM ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA

[2] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21287 USA

来源：

CELL | 2000年 / 101卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(00)80629-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：115 / 118

页数：4

共 20 条

[1] A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe [J].

Abbas, N ;

Lücking, CB ;

Ricard, S ;

Dürr, A ;

Bonifati, V ;

De Michele, G ;

Bouley, S ;

Vaughan, JR ;

Gasser, T ;

Marconi, R ;

Broussolle, E ;

Brefel-Courbon, C ;

Harhangi, BS ;

Oostra, AB ;

Fabrizio, E ;

Böhme, GA ;

Pradier, L ;

Wood, NW ;

Filla, A ;

Meco, G ;

Denefle, P ;

Agid, Y ;

Brice, A .

HUMAN MOLECULAR GENETICS, 1999, 8 (04) :567-574

[2] Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system [J].

Abeliovich, A ;

Schmitz, Y ;

Fariñas, I ;

Choi-Lundberg, D ;

Ho, WH ;

Castillo, PE ;

Shinsky, N ;

Verdugo, JMG ;

Armanini, M ;

Ryan, A ;

Hynes, M ;

Phillips, H ;

Sulzer, D ;

Rosenthal, A .

NEURON, 2000, 25 (01) :239-252

[3] The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease [J].

Clayton, DF ;

George, JM .

TRENDS IN NEUROSCIENCES, 1998, 21 (06) :249-254

[4] Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy [J].

Conway, KA ;

Lee, SJ ;

Rochet, JC ;

Ding, TT ;

Williamson, RE ;

Lansbury, PT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (02) :571-576

[5] Prospects for new restorative and neuroprotective treatments in Parkinson's disease [J].

Dunnett, SB ;

Björklund, A .

NATURE, 1999, 399 (6738) :A32-A39

[6] Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions [J].

Engelender, S ;

Kaminsky, Z ;

Guo, X ;

Sharp, AH ;

Amaravi, RK ;

Kleiderlein, JJ ;

Margolis, RL ;

Troncoso, JC ;

Lanahan, AA ;

Worley, PF ;

Dawson, VL ;

Dawson, TM ;

Ross, CA .

NATURE GENETICS, 1999, 22 (01) :110-114

[7] A Drosophila model of Parkinson's disease [J].

Feany, MB ;

Bender, WW .

NATURE, 2000, 404 (6776) :394-398

[8] Neuropathology of Parkinson's disease [J].

Forno, LS .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1996, 55 (03) :259-272

[9] NOS knockouts and neuroprotection [J].

Grünewald, T ;

Beal, MF .

NATURE MEDICINE, 1999, 5 (12) :1354-1355

[10] MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons [J].

Kowall, NW ;

Hantraye, P ;

Brouillet, E ;

Beal, MF ;

McKee, AC ;

Ferrante, RJ .

NEUROREPORT, 2000, 11 (01) :211-213

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