On the movements of nuclear components in living cells

被引:29
作者
Bubulya, PA [1 ]
Spector, DL [1 ]
机构
[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
chromatin domains; gene expression machinery; DNA repair; nuclear bodies; live cell microscopy;
D O I
10.1016/j.yexcr.2004.03.018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The use of GFP fusion proteins has dramatically changed our view of how the cell nucleus is organized and how functions are carried out. in this review we focus on recent advances related to the dynamics of chromatin domains, as well as the dynamics of nuclear proteins and several nuclear organelles. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:4 / 11
页数:8
相关论文
共 55 条
[1]   The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly [J].
Ahmad, K ;
Henikoff, S .
MOLECULAR CELL, 2002, 9 (06) :1191-1200
[2]   Dynamic behavior of transcription factors on a natural promoter in living cells [J].
Becker, M ;
Baumann, C ;
John, S ;
Walker, DA ;
Vigneron, M ;
McNally, JG ;
Hager, GL .
EMBO REPORTS, 2002, 3 (12) :1188-1194
[3]   Dynamics of chromatin, proteins, and bodies within the cell nucleus [J].
Belmont, A .
CURRENT OPINION IN CELL BIOLOGY, 2003, 15 (03) :304-310
[4]   Chromosome position: Now, where was I? [J].
Bickmore, WA ;
Chubb, JR .
CURRENT BIOLOGY, 2003, 13 (09) :R357-R359
[5]   Nucleolar components involved in ribosome biogenesis cycle between the nucleolus and nucleoplasm in interphase cells [J].
Chen, DY ;
Huang, S .
JOURNAL OF CELL BIOLOGY, 2001, 153 (01) :169-176
[6]   Maintenance of stable heterochromatin domains by dynamic HP1 binding [J].
Cheutin, T ;
McNairn, AJ ;
Jenuwein, T ;
Gilbert, DM ;
Singh, PB ;
Misteli, T .
SCIENCE, 2003, 299 (5607) :721-725
[7]   Cajal body-specific small nuclear RNAs:: a novel class of 2′-O-methylation and pseudouridylation guide RNAs [J].
Darzacq, X ;
Jády, BE ;
Verheggen, C ;
Kiss, AM ;
Bertrand, E ;
Kiss, T .
EMBO JOURNAL, 2002, 21 (11) :2746-2756
[8]   Visualizing RNA molecules inside the nucleus of living cells [J].
Dirks, RW ;
Molenaar, C ;
Tanke, HJ .
METHODS, 2003, 29 (01) :51-57
[9]   A kinetic framework for a mammalian RNA polymerase in vivo [J].
Dundr, M ;
Hoffmann-Rohrer, U ;
Hu, QY ;
Grummt, I ;
Rothblum, LI ;
Phair, RD ;
Misteli, T .
SCIENCE, 2002, 298 (5598) :1623-1626
[10]   Quantitative imaging of pre-mRNA splicing factors in living cells [J].
Eils, R ;
Gerlich, D ;
Tvaruskó, W ;
Spector, DL ;
Misteli, T .
MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (02) :413-418