ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome

被引:162
作者
Croft, L
Schandorff, S
Clark, F
Burrage, K
Arctander, P
Mattick, JS [1 ]
机构
[1] Univ Queensland, ARC Special res Ctr Mol & Cellular Biol, Brisbane, Qld, Australia
[2] Univ Queensland, Dept Math, Brisbane, Qld, Australia
[3] Univ Copenhagen, Dept Evolut Biol, Copenhagen, Denmark
关键词
D O I
10.1038/74153
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:340 / 341
页数:2
相关论文
共 12 条
[1]   Biochemistry and regulation of pre-mRNA splicing [J].
Adams, MD ;
Rudner, DZ ;
Rio, DC .
CURRENT OPINION IN CELL BIOLOGY, 1996, 8 (03) :331-339
[2]   ALTERNATIVE SPLICING - A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES [J].
BREITBART, RE ;
ANDREADIS, A ;
NADALGINARD, B .
ANNUAL REVIEW OF BIOCHEMISTRY, 1987, 56 :467-495
[3]   Directing alternative splicing: Cast and scenarios [J].
Chabot, B .
TRENDS IN GENETICS, 1996, 12 (11) :472-478
[4]   RNA-triggered gene silencing [J].
Fire, A .
TRENDS IN GENETICS, 1999, 15 (09) :358-363
[5]   Alternate polyadenylation in human mRNAs: A large-scale analysis by EST clustering [J].
Gautheret, D ;
Poirot, O ;
Lopez, F ;
Audic, S ;
Claverie, JM .
GENOME RESEARCH, 1998, 8 (05) :524-530
[6]   WHY GENES IN PIECES [J].
GILBERT, W .
NATURE, 1978, 271 (5645) :501-501
[7]   Alternative splicing of human genes -: more the rule than the exception? [J].
Hanke, J ;
Brett, D ;
Zastrow, I ;
Aydin, A ;
Delbrück, S ;
Lehmann, G ;
Luft, F ;
Reich, J ;
Bork, P .
TRENDS IN GENETICS, 1999, 15 (10) :389-390
[8]   RNA processing and the evolution of eukaryotes [J].
Herbert, A ;
Rich, A .
NATURE GENETICS, 1999, 21 (03) :265-269
[9]   INTRONS - EVOLUTION AND FUNCTION [J].
MATTICK, JS .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 1994, 4 (06) :823-831
[10]  
MCKEOWN M, 1992, ANNU REV CELL BIOL, V8, P133, DOI 10.1146/annurev.cellbio.8.1.133