Drosophila immunity

被引：198

作者：

Hoffmann, JA

Reichhart, JM

机构：

[1] Institut de Biologie Moléculaire et Cellulaire (IBMC), Centre National de la Recherche Scientifique (CNRS), 15 rue René Descartes

来源：

TRENDS IN CELL BIOLOGY | 1997年 / 7卷 / 08期

关键词：

D O I：

10.1016/S0962-8924(97)01087-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Septic injury induces in Drosophila the rapid and transient transcription of several genes encoding potent antimicrobial peptides. Significant structural and functional similarities exist between the injury-induced signalling cascades leading to antimicrobial peptide gene expression in Drosophila and cytokine-induced expression of mammalian acute-phase proteins. Here, the authors discuss their understanding of these pathways and their relationships to those found in mammalian cells. They also analyse non-self recognition and the role of blood cells in Drosophila host defence.

引用

页码：309 / 316

页数：8

共 70 条

[1] MOLECULAR-CLONING, SEQUENCING, AND CHARACTERIZATION OF CDNA FOR SARCOTOXIN-IIA, AN INDUCIBLE ANTIBACTERIAL PROTEIN OF SARCOPHAGA-PEREGRINA (FLESH FLY) [J].

ANDO, K ;

NATORI, S .

BIOCHEMISTRY, 1988, 27 (05) :1715-1721

[2] IDENTIFICATION OF EARLY GENES IN THE DROSOPHILA IMMUNE-RESPONSE BY PCR-BASED DIFFERENTIAL DISPLAY - THE ATTACIN-A GENE AND THE EVOLUTION OF ATTACIN-LIKE PROTEINS [J].

ASLING, B ;

DUSHAY, MS ;

HULTMARK, D .

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1995, 25 (04) :511-518

[3]

BAEUERLE PA, 1994, ANNU REV IMMUNOL, V12, P141, DOI 10.1146/annurev.immunol.12.1.141

[4] A conserved signaling pathway: The Drosophila Toll-Dorsal pathway [J].

Belvin, MP ;

Anderson, KV .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1996, 12 :393-416

[5] Crystal structure of coagulogen, the clotting protein from horseshoe crab: A structural homologue of nerve growth factor [J].

Bergner, A ;

Oganessyan, V ;

Muta, T ;

Iwanaga, S ;

Typke, D ;

Huber, R ;

Bode, W .

EMBO JOURNAL, 1996, 15 (24) :6789-6797

[6]

BOMAN HG, 1995, ANNU REV IMMUNOL, V13, P61, DOI 10.1146/annurev.iy.13.040195.000425

[7] INDUCIBLE ANTIBACTERIAL DEFENCE SYSTEM IN DROSOPHILA [J].

BOMAN, HG ;

NILSSON, I ;

RASMUSON, B .

NATURE, 1972, 237 (5352) :232-+

[8]

BROEKAERT WF, 1995, PLANT PHYSIOL, V108, P1353, DOI [10.1104/pp.108.4.1353, 10.1016/j.chiabu.2021.105188, 10.1016/j.coelec.2021.100721]

[9] Enlarged scale chemical synthesis and range of activity of drosocin, an O-glycosylated antibacterial peptide of Drosophila [J].

Bulet, P ;

Urge, L ;

Ohresser, S ;

Hetru, C ;

Otvos, L .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1996, 238 (01) :64-69

[10] INSECT IMMUNITY - THE INDUCIBLE ANTIBACTERIAL PEPTIDE DIPTERICIN CARRIES 2 O-GLYCANS NECESSARY FOR BIOLOGICAL-ACTIVITY [J].

BULET, P ;

HEGY, G ;

LAMBERT, J ;

VANDORSSELAER, A ;

HOFFMANN, JA ;

HETRU, C .

BIOCHEMISTRY, 1995, 34 (22) :7394-7400

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