Organic reactions in low melting mixtures based on carbohydrates and L-carnitine-a comparison

被引：149

作者：

Ilgen, Florian ^{[1
]}

Koenig, Burkhard ^{[1
]}

机构：

[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 06期

关键词：

UREA-SALT MIXTURES; IONIC LIQUIDS; REGIOSELECTIVE SYNTHESIS; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITION; SUPERCRITICAL FLUIDS; GREEN SOLVENTS; HECK REACTION; CATALYST; PALLADIUM;

D O I：

10.1039/b816551c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new L-carnitine/urea melt was developed and compared to previously reported sugar and sugar alcohol melts using several organic reactions for benchmarking. Physicochemical properties of the new L-carnitine melt, including the melting point and the polarity were determined by differential scanning calorimetry (DSC) and solvatochromatic measurements, respectively. The L-carnitine melt shows a very high polarity. Heck and Sonogashira cross-couplings, Diels-Alder reactions and Cu-catalysed 1,3-dipolar cycloadditions proceed cleanly in sugar and L-carnitine based melts, but the applicability of L-carnitine melts for standard organic reactions is limited by their lower thermal stability.

引用

页码：848 / 854

页数：7

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