Postinterventional subarachnoid haemorrhage after endovascular stroke treatment with stent retrievers

被引:43
作者
Nikoubashman, Omid [1 ,2 ]
Reich, Arno [3 ]
Pjontek, Rastislav [1 ]
Jungbluth, Michael [3 ]
Wiesmann, Martin [1 ]
机构
[1] Uniklin Aachen, Klin Diagnost & Intervent Neuroradiol, D-52074 Aachen, Germany
[2] Forschungszentrum Julich, Inst Neurosci & Med 4, D-52425 Julich, Germany
[3] Uniklin Aachen, Neurol Klin, D-52074 Aachen, Germany
关键词
Stroke; Postinterventional CT; Hyperdensity; Subarachnoid haemorrhage; Mechanical recanalization; ACUTE ISCHEMIC-STROKE; MECHANICAL THROMBECTOMY; CORONARY-ANGIOGRAPHY; SOLITAIRE STENT; RECANALIZATION;
D O I
10.1007/s00234-014-1424-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of this paper is to investigate the clinical significance of postinterventional subarachnoid hyperdensities (PSH) after endovascular mechanical thrombectomy in acute ischemic stroke. We analysed clinical and radiological data of 113 consecutive patients who received postinterventional CT scans within 4.5 h after mechanical thrombectomy. PSH was present in 27 of 113 patients (24 %). Extravasation of contrast agent was observed during intervention in only 6 of 27 cases (22 %). There was consecutive haemorrhagic transformation in four patients with PSH (p = 0.209, Fisher's exact test). Preinterventional predictors for the occurrence of PSH in our series were a long interval between clinical onset and recanalization (p = 0.028), a long procedure time (p = 0.010), and a high number of recanalization attempts (p = 0.001). PSH had no significant impact on clinical outcome (modified Rankin Scale) at discharge (p = 0.419) or at 3 months (p = 0.396). There were no significant correlations between PSH and thrombectomy devices (Solitaire: p = 0.433, Trevo Pro: p = 0.124). PSH after endovascular mechanical thrombectomy in acute ischemic stroke are likely to occur in complicated cases in which more than one revascularisation attempt is performed. PSH per se do not appear to be associated with an impaired clinical outcome or an elevated risk for consecutive haemorrhage.
引用
收藏
页码:1087 / 1096
页数:10
相关论文
共 19 条
[1]   Characteristics of compounds that cross the blood-brain barrier [J].
Banks, William A. .
BMC NEUROLOGY, 2009, 9
[2]  
Brockmann C, 2010, CLIN NEURORADIOL, V20, P231, DOI 10.1007/s00062-010-0036-3
[3]   Endovascular Treatment of Acute Intracerebral Artery Occlusions with the Solitaire Stent: Single-Centre Experience with 108 Recanalization Procedures [J].
Dorn, F. ;
Stehle, S. ;
Lockau, H. ;
Zimmer, C. ;
Liebig, T. .
CEREBROVASCULAR DISEASES, 2012, 34 (01) :70-77
[4]   Differences in endothelial injury after balloon angioplasty, insertion of balloon-expanded stents or release of self-expanding stents: An electron microscopic experimental study [J].
Harnek, J ;
Zoucas, E ;
Carlemalm, E ;
Cwikiel, W .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 1999, 22 (01) :56-61
[5]  
Khan SM, 2014, SAGE OPEN MED CASE R, V2
[6]  
Kurre W, 2014, NEURORADIOLOGY
[7]   Hyperattenuated Intracerebral Lesions after Mechanical Recanalization in Acute Stroke [J].
Lummel, N. ;
Schulte-Altedorneburg, G. ;
Bernau, C. ;
Pfefferkorn, T. ;
Patzig, M. ;
Janssen, H. ;
Opherk, C. ;
Brueckmann, H. ;
Linn, J. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2014, 35 (02) :345-351
[8]   Solitaire FR thrombectomy system: immediate results in 56 consecutive acute ischemic stroke patients [J].
Machi, Paolo ;
Costalat, Vincent ;
Lobotesis, Kyriakos ;
Maldonado, Igor Lima ;
Vendrell, Jean Francois ;
Riquelme, Carlos ;
Bonafe, Alain .
JOURNAL OF NEUROINTERVENTIONAL SURGERY, 2012, 4 (01) :62-66
[9]   t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes [J].
Niego, Be'eri ;
Freeman, Roxann ;
Puschmann, Till B. ;
Turnley, Ann M. ;
Medcalf, Robert L. .
BLOOD, 2012, 119 (20) :4752-4761
[10]   Clinical significance of post-interventional cerebral hyperdensities after endovascular mechanical thrombectomy in acute ischaemic stroke [J].
Nikoubashman, Omid ;
Reich, Arno ;
Gindullis, Mirco ;
Frohnhofen, Katharina ;
Pjontek, Rastislav ;
Brockmann, Marc-Alexander ;
Schulz, Joerg B. ;
Wiesmann, Martin .
NEURORADIOLOGY, 2014, 56 (01) :41-50