The many faces of tumor necrosis factor in stroke

被引：333

作者：

Hallenbeck, JM ^{[1
]}

机构：

[1] NINDS, Stroke Branch, NIH, Bethesda, MD 20892 USA

来源：

NATURE MEDICINE | 2002年 / 8卷 / 12期

关键词：

D O I：

10.1038/nm1202-1363

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cytokine, TNF, participates in virtually every aspect of stroke. Its effects, however, often appear contradictory. Analysis of the current model for TNF receptor signaling and TNF interactions with other stroke mediators helps to resolve some of these apparent discrepancies.

引用

收藏

页码：1363 / 1368

页数：6

相关论文

共 78 条

[1]

[Anonymous], 1999, Neurology, V53, P457

[2] Cyclooxygenase-2 inhibitor NS-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity [J].

Araki, E ;

Forster, C ;

Dubinsky, JM ;

Ross, ME ;

Iadecola, C .

STROKE, 2001, 32 (10) :2370-2375

[3] ACTIVATION OF DNA-BINDING ACTIVITY IN AN APPARENTLY CYTOPLASMIC PRECURSOR OF THE NF-KAPPA-B TRANSCRIPTION FACTOR [J].

BAEUERLE, PA ;

BALTIMORE, D .

CELL, 1988, 53 (02) :211-217

[4]

Becher H, 2000, J Epidemiol Biostat, V5, P277

[5] A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells [J].

Black, RA ;

Rauch, CT ;

Kozlosky, CJ ;

Peschon, JJ ;

Slack, JL ;

Wolfson, MF ;

Castner, BJ ;

Stocking, KL ;

Reddy, P ;

Srinivasan, S ;

Nelson, N ;

Boiani, N ;

Schooley, KA ;

Gerhart, M ;

Davis, R ;

Fitzner, JN ;

Johnson, RS ;

Paxton, RJ ;

March, CJ ;

Cerretti, DP .

NATURE, 1997, 385 (6618) :729-733

[6] Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia [J].

Botchkina, GI ;

Meistrell, ME ;

Botchkina, IL ;

Tracey, KJ .

MOLECULAR MEDICINE, 1997, 3 (11) :765-781

[7] Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors [J].

Bruce, AJ ;

Boling, W ;

Kindy, MS ;

Peschon, J ;

Kraemer, PJ ;

Carpenter, MK ;

Holtsberg, FW ;

Mattson, MP .

NATURE MEDICINE, 1996, 2 (07) :788-794

[8] Down-regulation of CD28 expression by TNF-α [J].

Bryl, E ;

Vallejo, AN ;

Weyand, CM ;

Goronzy, JJ .

JOURNAL OF IMMUNOLOGY, 2001, 167 (06) :3231-3238

[9] A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling [J].

Chan, FKM ;

Chun, HJ ;

Zheng, LX ;

Siegel, RM ;

Bui, KL ;

Lenardo, MJ .

SCIENCE, 2000, 288 (5475) :2351-2354

[10]

CHAO CC, 1995, CRIT REV NEUROBIOL, V9, P189

← 1 2 3 4 5 6 7 8 →