Mining Biological Pathways Using WikiPathways Web Services

被引：91

作者：

Kelder, Thomas

Pico, Alexander R.

Hanspers, Kristina

van Iersel, Martijn P.

Evelo, Chris

Conklin, Bruce R.

机构：

[1] Gladstone Institute of Cardiovascular Disease, San Francisco, CA

[2] Department of Medicine and Molecular, Department of Cellular Pharmacology, University of California San Francisco, San Francisco, CA

[3] Department of Bioinformatics - BiGCat, Maastricht University, Maastricht

来源：

PLOS ONE | 2009年 / 4卷 / 07期

关键词：

FEATURES; NETWORKS; GENES;

D O I：

10.1371/journal.pone.0006447

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

WikiPathways is a platform for creating, updating, and sharing biological pathways [1]. Pathways can be edited and downloaded using the wiki-style website. Here we present a SOAP web service that provides programmatic access to WikiPathways that is complementary to the website. We describe the functionality that this web service offers and discuss several use cases in detail. Exposing WikiPathways through a web service opens up new ways of utilizing pathway information and assisting the community curation process.

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