Methylation matters: a new spin on maspin

被引:26
作者
Costello, JF [1 ]
Vertino, PM
机构
[1] Univ Calif San Francisco, Dept Neurol Surg, Brain Tumor Res Ctr, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, UCSF Comprehens Canc Ctr, San Francisco, CA 94143 USA
[3] Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
[4] Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA
关键词
D O I
10.1038/ng0602-123
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The theory that DNA methylation controls tissue-specific gene expression has remained controversial despite being frequently cited for more than 25 years. A new study shows a pristine example of methylation and gene expression that is cell-type-restricted, although questions about causality persist.
引用
收藏
页码:123 / 124
页数:2
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