Molecular mechanisms of inherited insulin resistance

被引：15

作者：

Baynes, KCR

Whitehead, J

Krook, A

ORahilly, S

机构：

[1] UNIV CAMBRIDGE,DEPT MED,CAMBRIDGE CB2 2QQ,ENGLAND

[2] UNIV CAMBRIDGE,DEPT CLIN BIOCHEM,CAMBRIDGE,ENGLAND

[3] KAROLINSKA INST,KAROLINSKA HOSP,DEPT CLIN PHYSIOL,S-10401 STOCKHOLM,SWEDEN

来源：

QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS | 1997年 / 90卷 / 09期

关键词：

D O I：

10.1093/qjmed/90.9.557

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：557 / 562

页数：6

共 49 条

[1] INSULIN RESISTANCE DUE TO MUTATIONS OF THE INSULIN-RECEPTOR GENE - AN OVERVIEW [J].

ACCILI, D ;

CAMA, A ;

BARBETTI, F ;

KADOWAKI, H ;

KADOWAKI, T ;

TAYLOR, SI .

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1992, 15 (11) :857-864

[2] A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling - Evidence from transfection studies [J].

Almind, K ;

Inoue, G ;

Pedersen, O ;

Kahn, CR .

JOURNAL OF CLINICAL INVESTIGATION, 1996, 97 (11) :2569-2575

[3] AMINO-ACID POLYMORPHISMS OF INSULIN-RECEPTOR SUBSTRATE-1 IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS [J].

ALMIND, K ;

BJORBAEK, C ;

VESTERGAARD, H ;

HANSEN, T ;

ECHWALD, S ;

PEDERSEN, O .

LANCET, 1993, 342 (8875) :828-832

[4] ALTERNATIVE PATHWAY OF INSULIN SIGNALING IN MICE WITH TARGETED DISRUPTION OF THE IRS-1 GENE [J].

ARAKI, E ;

LIPES, MA ;

PATTI, ME ;

BRUNING, JC ;

HAAG, B ;

JOHNSON, RS ;

KAHN, CR .

NATURE, 1994, 372 (6502) :186-190

[5] CLONING OF A HUMAN INSULIN-STIMULATED PROTEIN-KINASE (ISPK-1) GENE AND ANALYSIS OF CODING REGIONS AND MESSENGER-RNA LEVELS OF THE ISPK-1 AND THE PROTEIN PHOSPHATASE-1 GENES IN MUSCLE FROM NIDDM PATIENTS [J].

BJORBAEK, C ;

VIK, TA ;

ECHWALD, SM ;

YANG, PY ;

VESTERGAARD, H ;

WANG, JP ;

WEBB, GC ;

RICHMOND, K ;

HANSEN, T ;

ERIKSON, RL ;

MIKLOS, GLG ;

COHEN, PTW ;

PEDERSEN, O .

DIABETES, 1995, 44 (01) :90-97

[6] GENETIC-VARIANTS IN PROMOTERS AND CODING REGIONS OF THE MUSCLE GLYCOGEN-SYNTHASE AND THE INSULIN-RESPONSIVE GLUT4 GENES IN NIDDM [J].

BJORBAEK, C ;

ECHWALD, SM ;

HUBRICHT, P ;

VESTERGAARD, H ;

HANSEN, T ;

ZIERATH, J ;

PEDERSEN, O .

DIABETES, 1994, 43 (08) :976-983

[7] Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles [J].

Bruning, JC ;

Winnay, J ;

BonnerWeir, S ;

Taylor, SI ;

Accili, D ;

Kahn, CR .

CELL, 1997, 88 (04) :561-572

[8] HUMAN GLUT4 MUSCLE-FAT GLUCOSE-TRANSPORTER GENE - CHARACTERIZATION AND GENETIC-VARIATION [J].

BUSE, JB ;

YASUDA, K ;

LAY, TP ;

SEO, TS ;

OLSON, AL ;

PESSIN, JE ;

KARAM, JH ;

SEINO, S ;

BELL, GI .

DIABETES, 1992, 41 (11) :1436-1445

[9] SEQUENCE OF THE HUMAN GLYCOGEN-ASSOCIATED REGULATORY SUBUNIT OF TYPE-1 PROTEIN PHOSPHATASE AND ANALYSIS OF ITS CODING REGION AND MESSENGER-RNA LEVEL IN MUSCLE FROM PATIENTS WITH NIDDM [J].

CHEN, YH ;

HANSEN, L ;

CHEN, MX ;

BJORBAEK, C ;

VESTERGAARD, H ;

HANSEN, T ;

COHEN, PTW ;

PEDERSEN, O .

DIABETES, 1994, 43 (10) :1234-1241

[10] MOLECULAR SCANNING OF INSULIN-RESPONSIVE GLUCOSE TRANSPORTER (GLUT4) GENE IN NIDDM SUBJECTS [J].

CHOI, WH ;

ORAHILLY, S ;

BUSE, JB ;

REES, A ;

MORGAN, R ;

FLIER, JS ;

MOLLER, DE .

DIABETES, 1991, 40 (12) :1712-1718

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