Silver staining method for demonstrating Lewy bodies in Parkinson's disease and argyrophilic oligodendrocytes in multiple system atrophy

被引：33

作者：

Braak, E ^{[1
]}

Braak, H ^{[1
]}

机构：

[1] Univ Frankfurt, Dept Anat, D-60590 Frankfurt, Germany

来源：

JOURNAL OF NEUROSCIENCE METHODS | 1999年 / 87卷 / 01期

关键词：

argyrophilic oligodendrocytes; cytoskeletal alterations; Lewy bodies; Lewy neurites; Lewy body disease; multiple system atrophy; Parkinson's disease; silver staining;

D O I：

10.1016/S0165-0270(98)00173-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A reliable and economical silver staining method is recommended for demonstration of Lewy bodies (LB) and Lewy neurites (LN) in Parkinson's disease (PD) and of argyrophilic oligodendrocytes in multiple system atrophy (MSA). The technique can be applied to routinely formalin-fixed autopsy material and does not require particular skills. It permits processing of frozen sections and sections from polyethylene glycol or paraffin embedded material. It takes advantage of the physical development of nucleation sites and thereby permits tight control of the entire staining procedure. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：111 / 115

页数：5

共 29 条

[1] IMMUNOHISTOCHEMICAL EXPRESSION OF MICROTUBULE-ASSOCIATED PROTEIN-5 (MAP5) IN GLIAL-CELLS IN MULTIPLE SYSTEM ATROPHY [J].