The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species

被引：541

作者：

Byrne, KP ^{[1
]}

Wolfe, KH ^{[1
]}

机构：

[1] Univ Dublin Trinity Coll, Dept Genet, Smurfit Inst, Dublin 2, Ireland

来源：

GENOME RESEARCH | 2005年 / 15卷 / 10期

关键词：

D O I：

10.1101/gr.3672305

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob)to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensively manually curated based on both sequence similarity and genomic context (synteny). We reconciled different laboratories' lists of paralogous Saccharomyces cerevisiae gene pairs formed by genome duplication (ohnologs), and present near-exhaustive lists of the ohnolog pairs retained in S. cerevisiae (551, including 22 previously unidentified), Saccharomyces castellii (599), and Candida glabrata (404).

引用

页码：1456 / 1461

页数：6

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