Is local intra-arterial fibrinolysis contraindicated in elderly patients with cerebral artery occlusion?

被引：9

作者：

Schumacher, M ^{[1
]}

Kraft, S ^{[1
]}

Siekmann, R ^{[1
]}

机构：

[1] Univ Freiburg, Dept Radiol, Neuroradiol Sect, D-79106 Freiburg, Germany

来源：

NEURORADIOLOGY | 1998年 / 40卷 / 12期

关键词：

cerebral artery occlusion; local intra-arterial fibrinolysis; age;

D O I：

10.1007/s002340050692

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Local intra-arterial fibrinolysis (LIF) is an effective treatment for selected patients in acute thromboembolic occlusion of the middle cerebral artery, vertebrobasilar system or ophthalmic artery. However, the risk/benefit ratio of thrombolysis in patient subgroups requires classification Advanced age has been regarded as a prognostic factor for poor clinical outcome. We report our experience with LIF in seven patients with a mean age of 79 years (range 76-83 years) who represented thromboembolic occlusion of the basilar, middle cerebral or pericallosal arteries. We discuss why advanced age need not contraindicate LIF.

引用

页码：822 / 826

页数：5

共 20 条

[1]

BERGDAMMER E, 1992, NEUROL RES, V14, P164, DOI 10.1080/01616412.1992.11740041

[2]

BOYSEN G, 1995, FIBRINOLYSIS S, V1, P29

[3] LOCAL INTRAARTERIAL THROMBOLYSIS FOR ACUTE STROKE IN THE CAROTID-ARTERY TERRITORIES [J].

CASTO, L ;

MOSCHINI, L ;

CAMERLINGO, M ;

GAZZANIGA, G ;

PARTZIGUAIN, T ;

BELLONI, G ;

MAMOLI, A .

ACTA NEUROLOGICA SCANDINAVICA, 1992, 86 (03) :308-311

[4] RECOMBINANT TISSUE PLASMINOGEN-ACTIVATOR IN ACUTE THROMBOTIC AND EMBOLIC STROKE [J].

DELZOPPO, GJ ;

POECK, K ;

PESSIN, MS ;

WOLPERT, SM ;

FURLAN, AJ ;

FERBERT, A ;

ALBERTS, MJ ;

ZIVIN, JA ;

WECHSLER, L ;

BUSSE, O ;

GREENLEE, R ;

BRASS, L ;

MOHR, JP ;

FELDMANN, E ;

HACKE, W ;

KASE, CS ;

BILLER, J ;

GRESS, D ;

OTIS, SM .

ANNALS OF NEUROLOGY, 1992, 32 (01) :78-86

[5] THROMBOLYTIC THERAPY IN CEREBROVASCULAR-DISEASE, (REPRINTED FROM CURRENT CONCEPTS OF CEREBROVASCULAR-DISEASE AND STROKE, 1988, VOL 23, PG 7-12) [J].

DELZOPPO, GJ .

STROKE, 1988, 19 (09) :1174-1179

[6] THROMBOLYTIC THERAPY IN STROKE - POSSIBILITIES AND HAZARDS [J].

DELZOPPO, GJ ;

ZEUMER, H ;

HARKER, LA .

STROKE, 1986, 17 (04) :595-607

[7] When is thrombolysis justified in patients with acute ischemic stroke? A bioethical perspective [J].

Furlan, AJ ;

Kanoti, G .

STROKE, 1997, 28 (01) :214-218

[8] INTRA-ARTERIAL THROMBOLYTIC THERAPY IMPROVES OUTCOME IN PATIENTS WITH ACUTE VERTEBROBASILAR OCCLUSIVE DISEASE [J].

HACKE, W ;

ZEUMER, H ;

FERBERT, A ;

BRUCKMANN, H ;

DELZOPPO, GJ .

STROKE, 1988, 19 (10) :1216-1222

[9]

KAPS M, 1991, THROMBOLYTIC THERAPY, P228

[10] INTRAARTERIEL LOCAL FIBRINOLYSIS OF BASILAR ARTERY THROMBOSIS IN ELDERLY PATIENTS [J].

KOLLIKOWSKI, H ;

EWERT, T ;

LEHMANN, HJ ;

SCHARAFINSKI, HW ;

SCHULZ, M .

AKTUELLE NEUROLOGIE, 1986, 13 (06) :201-206

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