The relevance of P2Y12-receptor gene variation for the outcome of clopidogrel-treated patients undergoing elective coronary stent implantation: A clinical follow-up

被引:6
作者
Bouman, Heleen J. [1 ,2 ,3 ,5 ]
van Werkum, Jochem W. [1 ,2 ,3 ]
Rudez, Goran [4 ]
Hackeng, Christian M. [2 ,5 ]
Leebeek, Frank W. G. [4 ]
ten Cate, Hugo [3 ]
ten Berg, Jurrien M. [1 ,2 ]
de Maat, Moniek P. M. [4 ]
机构
[1] St Antonius Hosp, Dept Cardiol, NL-3435 CM Nieuwegein, Netherlands
[2] St Antonius Hosp, St Antonius Ctr Platelet Funct Res, NL-3435 CM Nieuwegein, Netherlands
[3] Maastricht Univ Med Ctr, Cardiovasc Res Inst Maastricht, Dept Internal Med, Maastricht, Netherlands
[4] Erasmus Med Univ Ctr, Dept Hematol, Rotterdam, Netherlands
[5] St Antonius Hosp, Dept Clin Chem, NL-3435 CM Nieuwegein, Netherlands
关键词
PLATELET; EFFICACY;
D O I
10.1160/TH11-05-0306
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:189 / 191
页数:3
相关论文
共 15 条
[1]  
[Anonymous], DEF US TIMI TRIALS
[2]   Clopidogrel-Drug Interactions [J].
Bates, Eric R. ;
Lau, Wei C. ;
Angiolillo, Dominick J. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (11) :1251-1263
[3]   Paraoxonase-1 is a major determinant of clopidogrel efficacy [J].
Bouman, Heleen J. ;
Schoemig, Edgar ;
van Werkum, Jochem W. ;
Velder, Janna ;
Hackeng, Christian M. ;
Hirschhaeuser, Christoph ;
Waldmann, Christopher ;
Schmalz, Hans-Guenther ;
ten Berg, Jurrien M. ;
Taubert, Dirk .
NATURE MEDICINE, 2011, 17 (01) :110-U287
[4]   The influence of variation in the P2Y12 receptor gene on in vitro platelet inhibition with the direct P2Y12 antagonist cangrelor [J].
Bouman, Heleen J. ;
van Werkum, Jochem W. ;
Rudez, Goran ;
Leebeek, Frank W. G. ;
Kruit, Adrian ;
Hackeng, Christian M. ;
ten Berg, Jurrien M. ;
de Maat, Moniek P. M. ;
Ruven, Henk J. T. .
THROMBOSIS AND HAEMOSTASIS, 2010, 103 (02) :379-386
[5]   Comparison of Platelet Function Tests in Predicting Clinical Outcome in Patients Undergoing Coronary Stent Implantation [J].
Breet, Nicoline J. ;
van Werkum, Jochem W. ;
Bouman, Heleen J. ;
Kelder, Johannes C. ;
Ruven, Henk J. T. ;
Bal, Egbert T. ;
Deneer, Vera H. ;
Harmsze, Ankie M. ;
van der Heyden, Jan A. S. ;
Rensing, Benno J. W. M. ;
Suttorp, Maarten J. ;
Hackeng, Christian M. ;
ten Berg, Jurrien M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (08) :754-762
[6]   Clinical end points in coronary stent trials - A case for standardized definitions [J].
Cutlip, Donald E. ;
Windecker, Stephan ;
Mehran, Roxana ;
Boam, Ashley ;
Cohen, David J. ;
van Es, Gerrit-Anne ;
Steg, P. Gabriel ;
Morel, Marie-angele ;
Mauri, Laura ;
Vranckx, Pascal ;
McFadden, Eugene ;
Lansky, Alexandra ;
Hamon, Martial ;
Krucoff, Mitchell W. ;
Serruys, Patrick W. .
CIRCULATION, 2007, 115 (17) :2344-2351
[7]   Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects [J].
Fontana, P ;
Dupont, A ;
Gandrille, S ;
Bachelot-Loza, C ;
Reny, JL ;
Aiach, M ;
Gaussem, P .
CIRCULATION, 2003, 108 (08) :989-995
[8]   Ticagrelor for the treatment of arterial thrombosis [J].
Gurbel, Paul A. ;
Kereiakes, Dean J. ;
Tantry, Udaya S. .
EXPERT OPINION ON PHARMACOTHERAPY, 2010, 11 (13) :2251-2259
[9]   The use of amlodipine, but not of P-glycoprotein inhibiting calcium channel blockers is associated with clopidogrel poor-response [J].
Harmsze, Ankie M. ;
Robijns, Karen ;
Van Werkum, Jochem W. ;
Breet, Nicoline J. ;
Hackeng, Christian M. ;
ten Berg, Jurrien M. ;
Ruven, Hendrik J. T. ;
Klungel, Olaf H. ;
de Boer, Anthonius ;
Deneer, Vera H. M. .
THROMBOSIS AND HAEMOSTASIS, 2010, 103 (05) :920-925
[10]   Prasugrel: A novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile [J].
Jakubowski, Joseph A. ;
Winters, Kenneth J. ;
Naganuma, Hideo ;
Wallentin, Lars .
CARDIOVASCULAR DRUG REVIEWS, 2007, 25 (04) :357-374