Inherited epithelial transporter disorders -: an overview

被引：7

作者：

Bergeron, M. J. ^{[1
]}

Simonin, A. ^{[1
]}

Buerzle, M. ^{[1
]}

Hediger, M. A. ^{[1
]}

机构：

[1] Univ Bern, Inst Biochem & Mol Med, CH-3012 Bern, Switzerland

来源：

JOURNAL OF INHERITED METABOLIC DISEASE | 2008年 / 31卷 / 02期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1007/s10545-008-0861-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the late 1990s, the identification of transporters and transporter-associated genes progressed substantially due to the development of new cloning approaches such as expression cloning and, subsequently, to the implementation of the human genome project. Since then, the role of many transporter genes in human diseases has been elucidated. In this overview, we focus on inherited disorders of epithelial transporters. In particular, we review genetic defects of the genes encoding glucose transporters (SLC2 and SLC5 families) and amino acid transporters (SLC1, SLC3, SLC6 and SLC7 families).

引用

页码：178 / 187

页数：10

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