The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes

被引:59
作者
d'Onofrio, Alberto [2 ]
Manfredi, Piero [1 ]
Poletti, Piero [3 ,4 ]
机构
[1] Univ Pisa, Dept Stat & Appl Math, Pisa, Italy
[2] European Inst Oncol, Dept Expt Oncol, Milan, Italy
[3] Fdn Bruno Kessler, Trento, Italy
[4] Bocconi Univ, DONDENA Ctr Res Social Dynam, Milan, Italy
关键词
BEHAVIOR; GAME; INFORMATION; OSCILLATORITY; TRANSMISSION; AWARENESS; DYNAMICS; DISEASES; SPREAD; IMPACT;
D O I
10.1371/journal.pone.0045653
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
After a long period of stagnation, traditionally explained by the voluntary nature of the programme, a considerable increase in routine measles vaccine uptake has been recently observed in Italy after a set of public interventions aiming to promote MMR immunization, whilst retaining its voluntary aspect. To account for this take-off in coverage we propose a simple SIR transmission model with vaccination choice, where, unlike similar works, vaccinating behaviour spreads not only through the diffusion of "private'' information spontaneously circulating among parents of children to be vaccinated, which we call imitation, but also through public information communicated by the public health authorities. We show that public intervention has a stabilising role which is able to reduce the strength of imitation-induced oscillations, to allow disease elimination, and to even make the disease-free equilibrium where everyone is vaccinated globally attractive. The available Italian data are used to evaluate the main behavioural parameters, showing that the proposed model seems to provide a much more plausible behavioural explanation of the observed take-off of uptake of vaccine against measles than models based on pure imitation alone.
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页数:10
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