Does this have a familiar RING?

被引：474

作者：

Saurin, AJ ^{[1
]}

Borden, KLB ^{[1
]}

Boddy, MN ^{[1
]}

Freemont, PS ^{[1
]}

机构：

[1] DALHOUSIE UNIV, FAC MED, DEPT BIOCHEM, HALIFAX, NS B3H 4H7, CANADA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 06期

关键词：

D O I：

10.1016/0968-0004(96)10036-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The RING finger is a zinc-binding domain that is found in proteins from plants to humans, but whose function remains largely enigmatic, The domain itself is distinct from other zinc-finger motifs in terms of sequence homology, zinc-ligation scheme and three-dimensional structure. It appears that the RING is involved in mediating protein-protein interactions and in some cases multi-protein complexes, which might depend on the presence of other proteins and/or domains.

引用

页码：208 / 214

页数：7

共 49 条

[1] THE PHD FINGER - IMPLICATIONS FOR CHROMATIN-MEDIATED TRANSCRIPTIONAL REGULATION [J].

AASLAND, R ;

GIBSON, TJ ;

STEWART, AF .

TRENDS IN BIOCHEMICAL SCIENCES, 1995, 20 (02) :56-59

[2] STRUCTURE OF THE C3HC4 DOMAIN BY H-1-NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY - A NEW STRUCTURAL CLASS OF ZINC-FINGER [J].

BARLOW, PN ;

LUISI, B ;

MILNER, A ;

ELLIOTT, M ;

EVERETT, R .

JOURNAL OF MOLECULAR BIOLOGY, 1994, 237 (02) :201-211

[3]

BIOUKAR EB, 1993, BIOCHIMIE, V75, P303

[4] THE TRUNCATION THAT GENERATED THE V-CBL ONCOGENE REVEALS AN ABILITY FOR NUCLEAR TRANSPORT, DNA-BINDING AND ACUTE TRANSFORMATION [J].

BLAKE, TJ ;

HEATH, KG ;

LANGDON, WY .

EMBO JOURNAL, 1993, 12 (05) :2017-2026

[5] THE P53-ASSOCIATED PROTEIN MDM2 CONTAINS A NEWLY CHARACTERIZED ZINC-BINDING DOMAIN CALLED THE RING FINGER [J].

BODDY, MN ;

FREEMONT, PS ;

BORDEN, KLB .

TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (05) :198-199

[6] In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML [J].

Borden, KLB ;

Lally, JM ;

Martin, SR ;

OReilly, NJ ;

Solomon, E ;

Freemont, PS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (04) :1601-1606

[7] THE SOLUTION STRUCTURE OF THE RING FINGER DOMAIN FROM THE ACUTE PROMYELOCYTIC LEUKEMIA PROTO-ONCOPROTEIN PML [J].

BORDEN, KLB ;

BODDY, MN ;

LALLY, J ;

OREILLY, NJ ;

MARTIN, S ;

HOWE, K ;

SOLOMON, E ;

FREEMONT, PS .

EMBO JOURNAL, 1995, 14 (07) :1532-1541

[8]

BORDEN KLB, IN PRESS CURR OPIN S

[9] INVOLVEMENT OF CRAF1, A RELATIVE OF TRAF, IN CD40 SIGNALING [J].

CHENG, GH ;

CLEARY, AM ;

YE, ZS ;

HONG, DI ;

LEDERMAN, S ;

BALTIMORE, D .

SCIENCE, 1995, 267 (5203) :1494-1498

[10] CONTROL OF PROGRAMMED CELL-DEATH BY THE BACULOVIRUS GENES P35 AND IAP [J].

CLEM, RJ ;

MILLER, LK .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (08) :5212-5222

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