Transcription: Why are TAFs essential?

被引：13

作者：

Hampsey, M ^{[1
]}

Reinberg, D ^{[1
]}

机构：

[1] UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,DEPT BIOCHEM,DIV NUCLE ACIDS ENZYMOL,PISCATAWAY,NJ 08854

来源：

CURRENT BIOLOGY | 1997年 / 7卷 / 01期

关键词：

D O I：

10.1016/S0960-9822(06)00018-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The TAFs are transcription factors associated with the TATA binding protein, and until recently they were assumed to link specific activators to the general transcription machinery. Recent results suggest that the essential functions of TAFs are not as coactivators of transcription but as determinants of promoter selectivity.

引用

页码：R44 / R46

页数：3

共 21 条

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