microRNAs: Runts of the genome assert themselves

被引：204

作者：

Lai, EC ^{[1
]}

机构：

[1] Univ Calif Berkeley, Howard Hughes Med Inst, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

来源：

CURRENT BIOLOGY | 2003年 / 13卷 / 23期

关键词：

D O I：

10.1016/j.cub.2003.11.017

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

microRNAs form an abundant class of 21-22 nucleotide, non-coding RNA that is common to diverse species of multicellular life. Although they are currently the subject of intense, directed study, the path toward their discovery has been dominated by chance and serendipity. In this review, I examine how these tiny molecules have risen from genetic obscurity to scientific stardom, and discuss the emerging biological functions of these novel riboregulators.

引用

页码：R925 / R936

页数：12

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