A revised nomenclature for the human and rodent α-tubulin gene family

被引：46

作者：

Khodiyar, Varsha K.

Maltais, Lois J.

Sneddon, Katherine M. B.

Smith, Jennifer R.

Shimoyama, Mary

Cabral, Fernando

Dumontet, Charles

Dutcher, Susan K.

Harvey, Robert J.

Lafanechere, Laurence

Murray, John M.

Nogales, Eva

Piquemal, David

Stanchi, Fabio

Povey, Sue

Lovering, Ruth C.

机构：

[1] UCL, Dept Biol, HUGO Gene Nomenclature Comm, London NW1 2HE, England

[2] Jackson Lab, Mouse Genom Nomenclature Comm, Bar Harbor, ME 04609 USA

[3] Med Coll Wisconsin, Bioinformat Res Ctr, Milwaukee, WI 53226 USA

[4] Univ Texas, Sch Med, Dept Integrat Biol & Pharmacol, Houston, TX 77030 USA

[5] Univ Lyon 1, Fac Med, Lab Cytol Anal, Unite Inst Natl Sante & Rech Med 590, F-69373 Lyon 08, France

[6] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

[7] Sch Pharm, Dept Pharmacol, London WC1N1AX, England

[8] CEA Grenoble, Inst Rech Technol & Sci Vivant, Ctr Criblage Mol Bioact, F-38054 Grenoble, France

[9] Univ Penn, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

[10] Univ Calif Berkeley, Dept Mol & Cell Biol, Howard Hughes Med Inst, Berkeley, CA 94720 USA

[11] Univ Calif Berkeley, Lawrence Berkeley Lab, Berkeley, CA 94720 USA

[12] Skuld Tech Labs, Ctr Bioinformat, Montpellier, France

[13] Ctr A Lacassagne, CNRS, UMR6543, Inst Signaling Dev Biol & Canc Res, Nice, France

来源：

GENOMICS | 2007年 / 90卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.ygeno.2007.04.008

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

\An essential component of micrombules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：285 / 289

页数：5

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