共 156 条
Transcriptional regulation and transformation by MYC proteins
被引:911
作者:

Adhikary, S
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机构:
Univ Marburg, Inst Mol Biol & Tumour Res, D-35033 Marburg, Germany Univ Marburg, Inst Mol Biol & Tumour Res, D-35033 Marburg, Germany

Eilers, M
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机构:
Univ Marburg, Inst Mol Biol & Tumour Res, D-35033 Marburg, Germany Univ Marburg, Inst Mol Biol & Tumour Res, D-35033 Marburg, Germany
机构:
[1] Univ Marburg, Inst Mol Biol & Tumour Res, D-35033 Marburg, Germany
关键词:
D O I:
10.1038/nrm1703
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.
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页码:635 / 645
页数:11
相关论文
共 156 条
[1]
ONCOGENIC ACTIVITY OF THE C-MYC PROTEIN REQUIRES DIMERIZATION WITH MAX
[J].
AMATI, B
;
BROOKS, MW
;
LEVY, N
;
LITTLEWOOD, TD
;
EVAN, GI
;
LAND, H
.
CELL,
1993, 72 (02)
:233-245

AMATI, B
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND

BROOKS, MW
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND

LEVY, N
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND

LITTLEWOOD, TD
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND

EVAN, GI
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND

LAND, H
论文数: 0 引用数: 0
h-index: 0
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND
[2]
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
[J].
Arabi, A
;
Wu, SQ
;
Ridderstråle, K
;
Bierhoff, H
;
Shiue, C
;
Fatyol, K
;
Fahlén, S
;
Hydbring, P
;
Söderberg, O
;
Grummt, I
;
Larsson, LG
;
Wright, APH
.
NATURE CELL BIOLOGY,
2005, 7 (03)
:303-310

Arabi, A
论文数: 0 引用数: 0
h-index: 0
机构:
Sodertorns Hogskola, S-14189 Huddinge, Sweden Sodertorns Hogskola, S-14189 Huddinge, Sweden

Wu, SQ
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Ridderstråle, K
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Bierhoff, H
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Shiue, C
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Fatyol, K
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Fahlén, S
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Hydbring, P
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Söderberg, O
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Grummt, I
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Larsson, LG
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden

Wright, APH
论文数: 0 引用数: 0
h-index: 0
机构: Sodertorns Hogskola, S-14189 Huddinge, Sweden
[3]
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
[J].
Arnold, I
;
Watt, FM
.
CURRENT BIOLOGY,
2001, 11 (08)
:558-568

Arnold, I
论文数: 0 引用数: 0
h-index: 0
机构:
Imperial Canc Res Fund, London WC2A 3PX, England Imperial Canc Res Fund, London WC2A 3PX, England

Watt, FM
论文数: 0 引用数: 0
h-index: 0
机构:
Imperial Canc Res Fund, London WC2A 3PX, England Imperial Canc Res Fund, London WC2A 3PX, England
[4]
Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics
[J].
Aslanian, A
;
Iaquinta, PJ
;
Verona, R
;
Lees, JA
.
GENES & DEVELOPMENT,
2004, 18 (12)
:1413-1422

Aslanian, A
论文数: 0 引用数: 0
h-index: 0
机构:
MIT, Ctr Canc Res, Cambridge, MA 02139 USA MIT, Ctr Canc Res, Cambridge, MA 02139 USA

Iaquinta, PJ
论文数: 0 引用数: 0
h-index: 0
机构:
MIT, Ctr Canc Res, Cambridge, MA 02139 USA MIT, Ctr Canc Res, Cambridge, MA 02139 USA

Verona, R
论文数: 0 引用数: 0
h-index: 0
机构:
MIT, Ctr Canc Res, Cambridge, MA 02139 USA MIT, Ctr Canc Res, Cambridge, MA 02139 USA

Lees, JA
论文数: 0 引用数: 0
h-index: 0
机构:
MIT, Ctr Canc Res, Cambridge, MA 02139 USA MIT, Ctr Canc Res, Cambridge, MA 02139 USA
[5]
MAD - A HETERODIMERIC PARTNER FOR MAX THAT ANTAGONIZES MYC TRANSCRIPTIONAL ACTIVITY
[J].
AYER, DE
;
KRETZNER, L
;
EISENMAN, RN
.
CELL,
1993, 72 (02)
:211-222

AYER, DE
论文数: 0 引用数: 0
h-index: 0
机构: Division of Basic Sciences Fred Hutchinson Cancer Research Center Seattle

KRETZNER, L
论文数: 0 引用数: 0
h-index: 0
机构: Division of Basic Sciences Fred Hutchinson Cancer Research Center Seattle

EISENMAN, RN
论文数: 0 引用数: 0
h-index: 0
机构: Division of Basic Sciences Fred Hutchinson Cancer Research Center Seattle
[6]
A SWITCH FROM MYC-MAX TO MAD-MAX HETEROCOMPLEXES ACCOMPANIES MONOCYTE/MACROPHAGE DIFFERENTIATION
[J].
AYER, DE
;
EISENMAN, RN
.
GENES & DEVELOPMENT,
1993, 7 (11)
:2110-2119

AYER, DE
论文数: 0 引用数: 0
h-index: 0
机构: Division of Basic Sciences A2-025, Fred Hutchinson Cancer Res. Center, Seattle

EISENMAN, RN
论文数: 0 引用数: 0
h-index: 0
机构: Division of Basic Sciences A2-025, Fred Hutchinson Cancer Res. Center, Seattle
[7]
c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
[J].
Bahram, F
;
von der Lehr, N
;
Cetinkaya, C
;
Larsson, LG
.
BLOOD,
2000, 95 (06)
:2104-2110

Bahram, F
论文数: 0 引用数: 0
h-index: 0
机构: Swedish Univ Agr Sci, Dept Plant Biol, Uppsala Genet Ctr, S-75007 Uppsala, Sweden

von der Lehr, N
论文数: 0 引用数: 0
h-index: 0
机构: Swedish Univ Agr Sci, Dept Plant Biol, Uppsala Genet Ctr, S-75007 Uppsala, Sweden

Cetinkaya, C
论文数: 0 引用数: 0
h-index: 0
机构: Swedish Univ Agr Sci, Dept Plant Biol, Uppsala Genet Ctr, S-75007 Uppsala, Sweden

Larsson, LG
论文数: 0 引用数: 0
h-index: 0
机构: Swedish Univ Agr Sci, Dept Plant Biol, Uppsala Genet Ctr, S-75007 Uppsala, Sweden
[8]
c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism
[J].
Barsyte-Lovejoy, D
;
Mao, DYL
;
Penn, LZ
.
ONCOGENE,
2004, 23 (19)
:3481-3486

Barsyte-Lovejoy, D
论文数: 0 引用数: 0
h-index: 0
机构: Princess Margaret Hosp, Ontario Canc Inst, Div Cellular & Mol Biol, Toronto, ON M5G 2M9, Canada

Mao, DYL
论文数: 0 引用数: 0
h-index: 0
机构: Princess Margaret Hosp, Ontario Canc Inst, Div Cellular & Mol Biol, Toronto, ON M5G 2M9, Canada

Penn, LZ
论文数: 0 引用数: 0
h-index: 0
机构: Princess Margaret Hosp, Ontario Canc Inst, Div Cellular & Mol Biol, Toronto, ON M5G 2M9, Canada
[9]
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2F1 loss
[J].
Baudino, TA
;
Maclean, KH
;
Brennan, J
;
Parganas, E
;
Yang, CY
;
Aslanian, A
;
Lees, JA
;
Sherr, CJ
;
Roussel, MF
;
Cleveland, JL
.
MOLECULAR CELL,
2003, 11 (04)
:905-914

Baudino, TA
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Maclean, KH
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Brennan, J
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Parganas, E
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Yang, CY
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Aslanian, A
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Lees, JA
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Sherr, CJ
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Roussel, MF
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Cleveland, JL
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA
[10]
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
[J].
Baudino, TA
;
McKay, C
;
Pendeville-Samain, H
;
Nilsson, JA
;
Maclean, KH
;
White, EL
;
Davis, AC
;
Ihle, JN
;
Cleveland, JL
.
GENES & DEVELOPMENT,
2002, 16 (19)
:2530-2543

Baudino, TA
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

McKay, C
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Pendeville-Samain, H
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Nilsson, JA
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Maclean, KH
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

White, EL
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Davis, AC
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Ihle, JN
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA

Cleveland, JL
论文数: 0 引用数: 0
h-index: 0
机构: St Jude Childrens Res Hosp, Dept Biochem, Memphis, TN 38105 USA