Environmental enrichment prevents effects of dark-rearing in the rat visual cortex

被引：77

作者：

Bartoletti, A

Medini, P

Berardi, N

Maffei, L

机构：

[1] CNR, Ist Neurosci, I-56100 Pisa, Italy

[2] Scuola Normale Super Pisa, Pisa, Italy

[3] Univ Florence, Dipartimento Psicol, Florence, Italy

来源：

NATURE NEUROSCIENCE | 2004年 / 7卷 / 03期

关键词：

D O I：

10.1038/nn1201

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Environmental enrichment potentiates neural plasticity, enhancing acquisition and consolidation of memory traces(1). In the sensory cortices, after cortical circuit maturation and sensory function acquisition are completed, neural plasticity declines and the critical period 'closes'(2). In the visual cortex, this process can be prevented by dark-rearing, and here we show that environmental enrichment can promote physiological maturation and consolidation of visual cortical connections in dark-reared rats, leading to critical period closure.

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收藏

页码：215 / 216

页数：2

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