Sentinel function of broadly reactive human gamma delta T cells

被引：128

作者：

DeLibero, G

机构：

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 01期

关键词：

D O I：

10.1016/S0167-5699(97)80010-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The role of T-cell receptor (TCR) gamma delta cells in the immune response is still under much debate. In humans, a large subset of gamma delta T cells carrying TCR V gamma 9/V delta 2 broadly crossreact with a variety of phosphorylated nonpeptidic metabolites. Here, Gennaro De Libero suggests that these cell react rapidly with these ligands and may serve the function of sentinels.

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页码：22 / 26

页数：5

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