Glyoxalase I activity in human prostate cancer: A potential marker and importance in chemotherapy

被引：53

作者：

Davidson, SD ^{[1
]}

Cherry, JP ^{[1
]}

Choudhury, MS ^{[1
]}

Tazaki, H ^{[1
]}

Mallouh, C ^{[1
]}

Konno, S ^{[1
]}

机构：

[1] New York Med Coll, Dept Urol, Valhalla, NY 10595 USA

来源：

JOURNAL OF UROLOGY | 1999年 / 161卷 / 02期

关键词：

glyoxalase I; prostate cancer;

D O I：

10.1016/S0022-5347(01)61996-7

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: To provide information on the activity of Gly-I in prostate cancer. Materials and Methods: We performed qualitative Gly-I assay on prostate tissues. Results: Gly-I activity between prostate cancer and noncancerous specimens differed substantially and significantly, although such activity also varied somewhat among cancer specimens. Conclusions: Gly-I activity is indeed higher in cancerous than in noncancerous specimens, suggesting that it may play a role in prostate cancer homeostasis and survival.

引用

页码：690 / 691

页数：2

共 10 条

[1] GLYOXALASE ACTIVITIES IN TUMOR AND NONTUMOR HUMAN UROGENITAL TISSUES [J].