Should statin therapy be considered for patients with elevated C-reactive protein? The need for a definitive clinical trial

被引:33
作者
Ridker, PM [1 ]
机构
[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Cardiovasc Dis Prevent, Boston, MA 02115 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Leducq Ctr Cardiovasc Res, Boston, MA 02115 USA
关键词
D O I
10.1053/euhj.2001.2990
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2135 / 2137
页数:3
相关论文
共 16 条
[1]   Effect of statin therapy on C-reactive protein levels - The Pravastatin Inflammation/CRP Evaluation (PRINCE): A randomized trial and cohort study [J].
Albert, MA ;
Danielson, E ;
Rifai, N ;
Ridker, PM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 286 (01) :64-70
[2]   Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses [J].
Danesh, J ;
Whincup, P ;
Walker, M ;
Lennon, L ;
Thomson, A ;
Appleby, P ;
Gallimore, JR ;
Pepys, MB .
BMJ-BRITISH MEDICAL JOURNAL, 2000, 321 (7255) :199-204
[3]   Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels - Results of AFCAPS/TexCAPS [J].
Downs, JR ;
Clearfield, M ;
Weis, S ;
Whitney, E ;
Shapiro, DR ;
Beere, PA ;
Langendorfer, A ;
Stein, EA ;
Kruyer, W ;
Gotto, AM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (20) :1615-1622
[4]   Using cost-effectiveness analysis to target cholesterol reduction [J].
Garber, AM .
ANNALS OF INTERNAL MEDICINE, 2000, 132 (10) :833-835
[5]   Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) [J].
Gotto, AM ;
Whitney, E ;
Stein, EA ;
Shapiro, DR ;
Clearfield, M ;
Weis, S ;
Jou, JY ;
Langendörfer, A ;
Beere, A ;
Watson, DJ ;
Downs, JR ;
de Cani, JS .
CIRCULATION, 2000, 101 (05) :477-484
[6]   Statin therapy, lipid levels, C-reactive protein and the survival of patients with angiographically severe coronary artery disease [J].
Horne, BD ;
Muhlestein, JB ;
Carlquist, JF ;
Bair, TL ;
Madsen, TE ;
Hart, NI ;
Anderson, JL .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (06) :1774-1780
[7]   C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men -: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992 [J].
Koenig, W ;
Sund, M ;
Fröhlich, M ;
Fischer, HG ;
Löwel, H ;
Döring, A ;
Hutchinson, WL ;
Pepys, MB .
CIRCULATION, 1999, 99 (02) :237-242
[8]  
Ridker PM, 2001, CIRCULATION, V103, P1191
[9]   Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels [J].
Ridker, PM ;
Rifai, N ;
Pfeffer, MA ;
Sacks, FM ;
Moye, LA ;
Goldman, S ;
Flaker, GC ;
Braunwald, E .
CIRCULATION, 1998, 98 (09) :839-844
[10]   Evaluating novel cardiovascular risk factors: Can we better predict heart attacks? [J].
Ridker, PM .
ANNALS OF INTERNAL MEDICINE, 1999, 130 (11) :933-937