A role for secretory phospholipase A(2) and C-reactive protein in the removal of injured cells

被引：170

作者：

Hack, CE

Wolbink, GJ

Schalkwijk, C

Speijer, H

Hermens, WT

vandenBosch, H

机构：

[1] UNIV AMSTERDAM, CLIN & EXPT IMMUNOL LAB, NL-1066 CX AMSTERDAM, NETHERLANDS

[2] FREE UNIV AMSTERDAM HOSP, DEPT INTERNAL MED, AMSTERDAM, NETHERLANDS

[3] UNIV UTRECHT, CTR BIOMEMBRANES & LIPID ENZYMOL, NL-3584 CH UTRECHT, NETHERLANDS

[4] UNIV MAASTRICHT, CARDIOVASC RES INST, NL-6202 AZ MAASTRICHT, NETHERLANDS

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 03期

关键词：

D O I：

10.1016/S0167-5699(97)01002-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A(2) and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

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页码：111 / 115

页数：5

相关论文

共 48 条

[1] THE ACUTE-PHASE RESPONSE PROTECTS MICE FROM D-GALACTOSAMINE SENSITIZATION TO ENDOTOXIN AND TUMOR-NECROSIS-FACTOR-ALPHA [J].

ALCORN, JM ;

FIERER, J ;

CHOJKIER, M .

HEPATOLOGY, 1992, 15 (01) :122-129

[2] THE ACTIVATION OF POLYMORPHONUCLEAR NEUTROPHILS AND THE COMPLEMENT-SYSTEM DURING IMMUNOTHERAPY WITH RECOMBINANT INTERLEUKIN-2 [J].

BAARS, JW ;

HACK, CE ;

WAGSTAFF, J ;

EERENBERGBELMER, AJM ;

WOLBINK, GJ ;

THIJS, LG ;

VANSCHIJNDEL, RJMS ;

VANDERVALL, HLJA ;

PINEDO, HM .

BRITISH JOURNAL OF CANCER, 1992, 65 (01) :96-101

[3] PHYLOGENETIC ASPECTS OF C-REACTIVE PROTEIN AND RELATED PROTEINS [J].

BALTZ, ML ;

DEBEER, FC ;

FEINSTEIN, A ;

MUNN, EA ;

MILSTEIN, CP ;

FLETCHER, TC ;

MARCH, JF ;

TAYLOR, J ;

BRUTON, C ;

CLAMP, JR ;

DAVIES, AJS ;

PEPYS, MB .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1982, 389 (JUN) :49-75

[4] THE ACUTE-PHASE RESPONSE [J].

BAUMANN, H ;

GAULDIE, J .

IMMUNOLOGY TODAY, 1994, 15 (02) :74-80

[5]

CROWL RM, 1991, J BIOL CHEM, V266, P2647

[6] ACTIVATION OF THE COMPLEMENT-SYSTEM IN BABOONS CHALLENGED WITH LIVE ESCHERICHIA-COLI - CORRELATION WITH MORTALITY AND EVIDENCE FOR A BIPHASIC ACTIVATION PATTERN [J].

DEBOER, JP ;

CREASEY, AA ;

CHANG, A ;

ROEM, D ;

EERENBERG, AJM ;

HACK, CE ;

TAYLOR, FB .

INFECTION AND IMMUNITY, 1993, 61 (10) :4293-4301

[7] INFLAMMATION-INDUCED EXPRESSION OF SIALYL LEWIS X-CONTAINING GLYCAN STRUCTURES ON ALPHA-1-ACID GLYCOPROTEIN (OROSOMUCOID) IN HUMAN SERA [J].

DEGRAAF, TW ;

VANDERSTELT, ME ;

ANBERGEN, MG ;

VANDIJK, W .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (03) :657-666

[8] RELATION BETWEEN VARIOUS PHOSPHOLIPASE ACTIONS ON HUMAN RED-CELL MEMBRANES AND INTERFACIAL PHOSPHOLIPID PRESSURE IN MONOLAYERS [J].

DEMEL, RA ;

GEURTSVANKESSEL, WSM ;

ZWAAL, RFA ;

ROELOFSEN, B ;

VANDEENEN, LLM .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 406 (01) :97-107

[9]

DENNIS EA, 1994, J BIOL CHEM, V269, P13057

[10] PORE-FORMING PEPTIDES INDUCE RAPID PHOSPHOLIPID FLIP-FLOP IN MEMBRANES [J].

FATTAL, E ;

NIR, S ;

PARENTE, RA ;

SZOKA, FC .

BIOCHEMISTRY, 1994, 33 (21) :6721-6731

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