Predictive value of electron beam computed tomography of the coronary arteries - 19-month follow-up of 1173 asymptomatic subjects

被引：440

作者：

Arad, Y ^{[1
]}

Spadaro, LA ^{[1
]}

Goodman, K ^{[1
]}

LledoPerez, A ^{[1
]}

Sherman, S ^{[1
]}

Lerner, C ^{[1
]}

Guerci, AD ^{[1
]}

机构：

[1] ST FRANCIS HOSP,DEPT RADIOL,ROSLYN,NY 11576

来源：

CIRCULATION | 1996年 / 93卷 / 11期

关键词：

tomography; calcium; atherosclerosis; coronary disease; follow-up studies;

D O I：

10.1161/01.CIR.93.11.1951

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Coronary electron beam computed tomography (EBCT) detects atherosclerotic coronary artery disease by measuring calcium deposition in the walls of coronary arteries. EBCT-derived coronary artery calcium (CAC) scores correlate with the severity of underlying coronary artery disease. Methods and Results We followed 1173 asymptomatic patients who underwent EBCT between September 1993 and March 1994. During average follow-up of 19 months, 18 subjects had 26 cardiovascular events: 1 death, 7 myocardial infarctions, 8 coronary artery bypass graft procedures, 9 coronary angioplasties, and 1 nonhemorrhagic stroke. For CAC score thresholds of 100, 160, and 680, EBCT had sensitivities of 89%, 89%, and 50% and specificities of 77%, 52%, and 95%, respectively. Odds ratios ranged from 20.0 to 35.4 (P<.00001 for all). Conclusions Coronary EBCT predicts future atherosclerotic cardiovascular disease events in asymptomatic subjects.

引用

页码：1951 / 1953

页数：3

共 20 条

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